{"id":107,"date":"2023-10-25T15:22:13","date_gmt":"2023-10-25T08:22:13","guid":{"rendered":"https:\/\/conf.icgbio.ru\/csb\/?page_id=107"},"modified":"2023-10-25T15:25:02","modified_gmt":"2023-10-25T08:25:02","slug":"kochetov","status":"publish","type":"page","link":"https:\/\/conf.icgbio.ru\/csb\/members\/kochetov\/","title":{"rendered":"Prof. Dr. Alexey Kochetov"},"content":{"rendered":"

\"\"<\/p>\n

Institute of Cytology and Genetics SB RAS, Novosibirsk
\nProf. Dr. Alexey Kochetov<\/b><\/big><\/p>\n

 <\/p>\n

CURRICULUM VITAE<\/big><\/b><\/p>\n

Name:<\/b>
\nAlex V. Kochetov<\/p>\n

Address:<\/b>
\n10, pr. Lavrentieva,
\nInstitute of Cytology and Genetics,
\nNovosibirsk, 630090, Russia<\/p>\n

Affiliation:<\/b>
\nHead of the Plant Gene Engineering Laboratory,
\nInstitute of Cytology and Genetics,
\nRussian Academy of Sciences (Siberian Branch),
\nNovosibirsk, Russia<\/p>\n

Education:<\/b><\/p>\n

1991<\/b>
\nNovosibirsk State University, Department of Biology.<\/p>\n

1998<\/b>
\nPh.D. thesis: “mRNA sequence characteristics and expression of foreign genes in plant cells: experimental and computer analysis”, Novosibirsk, supervisors Prof., Dr.Sci V.K.Shumny, Dr.Sci. M.I.Rivkin<\/p>\n

2004<\/b>
\nAssociate Professor<\/p>\n

Skills:<\/b>
\nmolecular cloning, RNA-, DNA- and protein analysis, plant transgenesis, computer analysis of nucleotide sequences, bioinformatics, gene and mRNA organization<\/p>\n

Interests:<\/b>
\nmolecular genetics, gene engineering, biotechnology, bioinformatics<\/p>\n

Awards:<\/b>
\nBelyaev’s Prize Laureate in Genetics, 1999, Siberian Branch of Russian Academy of Science
\nChairman of society of young scientists of the Institute of Cytology and genetics (elected for 1999-2001 period). Vice-president of Society of young scientists of Siberian Division of Russian Academy of Sciences (biological division. elected for 1999-2001 period).<\/p>\n

Member of Organizing and Program Committees:<\/b>
\n2001, 2002<\/b>\u00a0Lavrentiev’s Conference of junior researchers, Novosibirsk, Russia
\n2006<\/b>\u00a0Pattern Recognition in Bioinformatics, Hong Kong
\n2006<\/b>\u00a0Bioinformatics in Genome Regulation and Structure, Novosibirsk, Russia<\/p>\n

Member of Bioinformatics Council, Siberian Branch of Russian Academy of Sciences<\/b><\/p>\n

Selected Publications and Manuscripts (total, 90):<\/b><\/p>\n

    \n
  1. Kochetov A.V.<\/b>\u00a0Alternative translation initiation sites and their impact to eukaryotic proteome. Russ. J. Mol. Biol. 2006 (in press).<\/li>\n
  2. Volkova O.A., Kochetov A.V.<\/b>, Titov S.E., Kolchanov N.A. Potential open reading frames within eukaryotic mRNA 5′-untranslated regions. \/\/ Russ. J. Biophysics. 2006 (in press)<\/li>\n
  3. Kolodiazhnaia IaS, Titov SE, Kochetov AV, Komarova ML, Romanova AV, Koval’ VS, Shumnyi VK Evaluation of salt tolerance in Nicotiana tabacum plants bearing an antisense suppressor of the proline dehydrogenase gene. Russ. J. Genetics. 2006 Feb;42(2):278-81<\/li>\n
  4. Kochetov A.V.<\/b>, Sarai A., Rogozin I.B., Shumny V.K., Kolchanov N.A. The role of alternative translation start sites in generation of human protein diversity \/\/ Mol. Genet. Genomics 2005. 273. 491-496.<\/li>\n
  5. Kochetov A.V.<\/b>\u00a0AUG codons at the beginning of protein coding sequences are frequent in eukaryotic mRNAs with a suboptimal start codon context. Bioinformatics. 2005. V.21. P.837-840.<\/li>\n
  6. Kochetov A.V.<\/b>, Sarai A. Translational polymorphism as a potential source of plant proteins variety in Arabidopsis thaliana \/\/ Bioinformatics. 2004. V.20. P.445-447.<\/li>\n
  7. Vishnevsky O.V., Avdeeva I.V., Kochetov A.V.<\/b>\u00a0Study of the specific contextual features of translation initiation and termination sites in Saccharomyces cerevisiae \/\/ In: Bioinformatics of genome regulation and structure. Ed. by N. Kolchanov and R. Hofestaedt, Kluwer AcademicPublishers, Boston\/Dordrecht\/London, 2004, pp. 213-222.<\/li>\n
  8. Matushkin Yu.G., Likhoshvai V.A., Kochetov A.V.<\/b>\u00a0Local secondary structure may be a critical characteristic influencing translation of unicellular organisms mRNA. \/\/ In: Bioinformatics Of Genome Regulation And Structure. Ed. By N. Kolchanov and R. Hofestaedt, Kluwer Academic Publishers, Boston\/Dordrecht\/London, 2004, pp. 103-114.<\/li>\n
  9. Pichueva A.G., Kochetov A.V.<\/b>, Milanesi L., Kondrakhin Yu.V., Kolchanov N.A. Correlations between sequence features of yeast genes functional regions and the level of expression \/\/ In: Bioinformatics Of Genome Regulation And Structure. Ed. By N. Kolchanov and R. Hofestaedt, Kluwer Academic Publishers, Boston\/Dordrecht\/London, 2004, pp. 125-132.<\/li>\n
  10. Trifonova EA, Komarova ML, Leonova NS, Shcherban AB, Kochetov AV, Malinovskii VI, Shumnyi VK. Transgenic potato (Solanum tuberosum L.) plants expressing the gene of secretory nuclease from Serratia marcescens. Dokl. Biochem. Biophys. 2004. V.394. P.39-41.<\/li>\n
  11. Kochetov A.V.<\/b>, Titov C.E., Kolodyazhnaya J.S., Komarova M.L., Koval V.S., Trifonova E.A., Shumny V.K. Increase in proline content and cytoplasmic osmotic pressure in transformed tobacco plants bearing antisense suppressor of proline dehydrogenase \/\/ Russ. J. Genetics. 2004. V.40. P. 282-285.<\/li>\n
  12. Kochetov A.V.<\/b>, Kolchanov N.A., Sarai A. Interrelations between the “strength” of translation start site and the sequence features of yeast mRNAs \/\/ Molecular Genetics & Genomics \/\/ 2003. V. 270. P. 442-447.<\/li>\n
  13. Kochetov A.V.<\/b>, Sarai A., Vorob’ev D.G., Kolchanov N.A. The context organization of functional regions in yeast genes with high-level expression \/\/ Russ. J. Mol. Biol. 2002. V. 36. P. 1026-1034.<\/li>\n
  14. Kochetov A.V.<\/b>, Sirnik O.A., Rogozin I.B., Glazko G.V., Komarova M.L., Shumny V.K. Context organization of mRNA 5′-untranslated regions of higher plants \/\/ Russ. J. Mol. Biol. 2002. V.36. P. 649-656.<\/li>\n
  15. Trifonova E.A., Komarova M.L., Sirnik O.A., Kochetov A.V.<\/b>, Shumny V.K. Transgenic tobacco (Nicotiana tabacum SR1) plants expressing the gene coding for Serratia marcescens nuclease \/\/ Russ. J. Genetics 2002. V.38. P.274-277.<\/li>\n
  16. Kochetov AV, Grigorovich D, Kolchanov NA, Sarai A. Database on mRNA-located eukaryotic expression signals influencing translation efficiency and specificity \/\/ Genome Informatics. Ser. 12. Edt: Matsuda et al. Universal Academy Press. Tokyo. Japan. 2001. P.492-493.<\/li>\n
  17. Titov I.I., Kochetov A.V.<\/b>, Kolchanov N.A., Sarai A. Revealing mRNA translational signals by primary and secondary structure analysis \/\/ Genome Informatics. Ser. 12. Edt: Matsuda et al. Universal Academy Press. Tokyo. Japan. 2001. P.447-448.<\/li>\n
  18. Kochetov A.V.<\/b>, Grigorovich D.A., Titov I.I., Vorob’ev D.G., Sirnik O.A., Vishnevsky O.V., Sarai A., Kolchanov N.A. mRNA-FAST (mRNA-Function, Activity, STructure) computer system \/\/ Russ. J. Mol. Biol. 2001. V.35. P. 1039-1047.<\/li>\n
  19. Rogozin I.B., Kochetov A.V.<\/b>, Kondrashov F.A., Koonin E.V., Milanezi L. Presence of ATG triplets in 5′ untranslated regions of eukaryotic cDNAs correlates with a “weak” context of the start codon \/\/ Bioinformatics. 2001. V. 17. P. 890-900.<\/li>\n
  20. Trifonova E.A., Kochetov A.V.<\/b>, Shumny V.K. Role of nucleases in plant physiology \/\/ Advances in Modern Biology (review). 2000. V.120. P.395-405.<\/li>\n
  21. Kochetov A.V.<\/b>, Ponomarenko M.P., Frolov A.S., Kisselev L.L., Kolchanov N.A. Prediction of eukaryotic mRNA translational properties \/\/ Bioinformatics J. 1999. V.15. P.704-712<\/li>\n
  22. Kolchanov N.A., Ponomarenko M.P., Kel A.E., Kondrakhin Ju.V., Frolov A.S., Kolpakov F.A., Goryachkovskaya T.N., Kel O.V., Ananko E.A., Ignatieva E.V., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Babenko V.V., Vorobiev D.V., Lavryushev S.V., Ponomarenko Yu.V., Kochetov A.V.<\/b>, Kolesov G.N., Podkolodny N.L., Milanesi L., Wingender E., Heinemeyer T., Solovyev V., Overton G.C Genexpress 1.0: an WWW-oriented intergartor for the databases and computer systems for studying the eukaryotic gene expression \/\/ Bioinformatics J. 1999. V.15. P.669-686.<\/li>\n
  23. Kochetov A.V.<\/b>, Pilugin M.V., Kolpakov F.A., Babenko V.N., Kolchanov N.A., Shumny V.K. 5’UTR of plant mRNAs: context of start AUG codon \/\/ Cytol. Genet. (Kiev) 1999. V.33. P. 3-9.<\/li>\n
  24. Kolchanov N.A., Ponomarenko M.P., Kel A.E., Kondrakhin Ju.V., Frolov A.S., Kolpakov F.A., Goryachkovskaya T.N., Kel O.V., Ananko E.A., Ignatieva E.V., Podkolodnaya O.A., Stepanenko I.L., Merkulova T.I., Babenko V.V., Vorobiev D.V., Lavryushev S.V., Ponomarenko Yu.V., Kochetov A.V.<\/b>, Kolesov G.N., Podkolodny N.L., Milanesi L., Wingender E., Heinemeyer T., Solovyev V., Overton G.C GeneExpress: integrator for the databases and computer systems for studying the eukaryotic gene expression \/\/ Biofizika (Moscow). 1999. V.44. P.837-841.<\/li>\n
  25. Kochetov A.V.<\/b>, Ischenko I.V., Vorobiev D.G., Kel A.E., Babenko V.N., Kisselev L.L., Kolchanov N.A. Eukaryotic mRNAs encoding abundant and scarce proteins are statistically dissimilar in many structural features \/\/ FEBS Lett. 1998. V.440. P.351-355.<\/li>\n
  26. Deineko E.V., Zagorskaya A.A., Filipenko E.A., Filipenko M.L., Komarova N.I., Kochetov A.V.<\/b>, Shumny V.K. instability of the gene NPTII expression in transgenic tobacco (Nicotiana tabacum L.) plants during inbreeding\/\/ Russ. J. Genetics. 1998. V.34. P.1212-1219. 27. Kolchanov N.A., Ponomarenko M.P., Kel A. E., Kondrakhin Yu. V., Frolov A. S., Kolpakov F. A., Kel O. V., Ananko E. A., Ignatieva E.V., Podkolodnaya O. A., Stepanenko I. L., Merkulova T. I., Babenko V. N., Vorobiev D.G, Lavryushev S.V., Ponomarenko Yu. V., Kochetov A. V., Kolesov G.B., Podkolodny N. L., Milanesi L., Wingender E., Heinemeyer T., Solovyev V.V. GeneExpress: a computer system for description, analysis, and recognition of regulatory sequences of the eukaryotic genome. \/\/ Proc. ISMB. 1998. V.6. P.95-104.<\/li>\n
  27. Kochetov A.V.<\/b>\u00a0, Shumny V.K. Influence of mRNA sequence characteristics on translation intiation in plant cells (review) \/\/ Advances in current biology (Moscow). 1998. V.118. P.756-773.<\/li>\n
  28. Gruntenko N.E., Kochetov A.V.<\/b>, Makarova K.S., Mishin V.P., Lukasheva V.V., Ptitsyn A.A., Kokoza V.A. Gene N\u044173EF of Drosophila melanogaster encodes a protein highly homologous to E1 subunit of human 2-oxoglutarate dehydrogenase \/\/ Russ. J. Genetics. 1997.V.33. P.32-37.<\/li>\n
  29. Kochetov A.V.<\/b>, Lukasheva V.V., Pilugin M.P., Konarova M.L., Deineko E.V., Rivkin M.I., McClean Ph., Shumny V.K. Exression of operons in plant cells \/\/ Cytology and Genetics (Kiev).1997. V.6. P.17-28.<\/li>\n
  30. Kel A.E., Kolchnov N.A., Romaschenko A.G., Ananko E.A., Ignatieva E.V., Merkulova T.I., Podkolodnaya O.A. Kochetov A.V.<\/b>, Stepanenko I.A., Kolpako F.A., Podkolodny N.L., Naumochkin A.A.. TRRD: database on transcriptional regulatory regions of eukaryotic genes \/\/ Russ. J. Mol. Biol. 1997. V.31. P.626-636.<\/li>\n
  31. Deineko E.V., Zagorskaya A.A., Filipenko E.A., Filipenko M.L., Novoselya T.V., Komarova M.L., Kochetov A.V.<\/b>, Shumny V.K. Instability of NPTII gene expression in the progeny of transgenic tobacco plants (Nicotiana tabacum L. and N.plumbaginifolia L.) \/\/ Biotechnology & Biotech.Equip. 1996. N4. P.89-92.<\/li>\n
  32. Kochetov A.V.<\/b>, Lukasheva V.V., Komarova M.L., Pilugin M.V., Deineko E.V., Rivkin M.I., Shumny V.K. Expression of model bicistrones in transgenic plants \/\/ Reports of Russian Academy of Sciences. 1996. V.349. P.549-552.<\/li>\n
  33. Rivkin M., Deineko E., Komarova M., Kochetov A., Malyshenko S., Talianskii M., Shumny V. Analysis of virus resistance of tobacco and alfalfa transgenic plants bearing human beta-interferon gene \/\/ Biotechnology & Biotech.Equip. 1995. N.1. P.40-44.<\/li>\n
  34. Deineko E.V., Zagorskaya A.A., Filipenko M.L., Kochetov A.V.<\/b>, Shumny V.K. Variability in expression of marker NPTII gene in generations of transgenic tobacco plants \/\/ Reports of Russian Academy of Sciences 1995. V.344. P.407-411.<\/li>\n
  35. Kochetov A.V.<\/b>, Lukasheva V.V., Filipenko M.L., Mertvetzov N.P., Rivkin M.I. Primary structure of coding sequence of the human pancreatic ribonuclease gene and its localization on chromosomes \/\/ Russ. J. Bioorg. Chem. 1995. V.21. P.691-694.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

    Institute of Cytology and Genetics SB RAS, Novosibirsk Prof. Dr. Alexey Kochetov   CURRICULUM VITAE Name: Alex V. Kochetov Address: 10, pr. Lavrentieva, Institute of Cytology and Genetics, Novosibirsk, 630090, Russia Affiliation: Head of the Plant Gene Engineering Laboratory, Institute … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":13,"featured_media":0,"parent":105,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"_links":{"self":[{"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/pages\/107"}],"collection":[{"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/users\/13"}],"replies":[{"embeddable":true,"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/comments?post=107"}],"version-history":[{"count":5,"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/pages\/107\/revisions"}],"predecessor-version":[{"id":112,"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/pages\/107\/revisions\/112"}],"up":[{"embeddable":true,"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/pages\/105"}],"wp:attachment":[{"href":"https:\/\/conf.icgbio.ru\/csb\/wp-json\/wp\/v2\/media?parent=107"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}