Scientific program » ISHG-2014

June 24,Tuesday The Exhibition Center of the SB RAS

INTERNATIONAL SYMPOSIUM “HUMAN GENETICS”

Co-chairpersons:
Prof. Valery Puzyrev, FSBI Research Institute of Medical Genetics, Tomsk, Russia
Prof. Mikhail Voevoda, FSBI Institute of Internal and Preventive Medicine SB RAMS, Novosibirsk, Russia

SECTION MEDICAL GENETICS
No	Author (s) and title of Talk	Timeline
Opening remark 9-00:9-10
1	A. Polyakov Research Centre of Medical Genetics of the Russian Academy of Medical Sciences, Moscow, Russia CASES OF AUTOSOMAL RECESSIVE PATHOLOGY IN A GROUP OF MUSCULAR DYSTROPHY X-LINKED TYPE OF INHERITANCE	9-10:9-50
2	I. Lebedev, A. Kashevarova, N. Skryabin FSBI Research Institute of Medical Genetics, Tomsk, Russia GENOME ARCHITECTURE AND CHROMOSOMAL DISEASES	9-50:10-10
3	N. Yudin ⁽¹⁾⁽²⁾, T. Mishakova ⁽¹⁾, V. Maksimov ⁽¹⁾⁽²⁾, V. Gafarov ⁽²⁾, S. Malyutina ⁽²⁾, M. Voevoda ⁽¹⁾⁽²⁾ ⁽¹⁾ Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia ⁽²⁾ Institute of Internal and Preventive Medicine SB RAMS, Novosibirsk, Russia FSBI Internal and Preventive Medicine SB RAMS, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation ASSOCIATION OF THE DOPAMINE RECEPTOR D4 (DRD4) GENE POLYMORPHISM WITH CARDIOVASCULAR DISEASE RISK FACTORS	10-10:10-30
4	N. Skryabin, I. Lebedev FSBI Research Institute of Medical Genetics, Tomsk, Russia SOMATIC GENOME VARIABILITY AND MORPHOLOGICAL HETEROGENEITY OF BREAST CANCER	10:30-10:50
Coffee /tea break 10-50:11-00
5	M. Nazarenko, A. Markov, A. Sleptcov, I. Lebedev, N. Skryabin, A. Kashevarova, A. Frolov, O. Barbarash, V. Puzyrev FSBI Research Institute of Medical Genetics, Tomsk, Russia GENOME-WIDE PROFILING OF DNA COPY NUMBER AND METHYLATION IN ATHEROSCLEROSIS	11-00:11-20
6	R. Goncharova, N. Nikitchenko, V. Ramaniuk, N. Savina, T. Kuzhir Institute of Genetics ND Cytology, National Academy of Sciences of Belarus, Minsk, Republic of Belarus XPD, XRCC1, OGG1 AND ERCC6 POLYMORPHISMS AND HUMAN LIFESPAN	11-20:11-40
7	I. Goncharova ⁽¹⁾⁽²⁾, O. Makeeva ⁽¹⁾⁽²⁾, N. Tarasenko ⁽¹⁾, A. Markov ⁽¹⁾, S. Buikin ⁽¹⁾, V. Puzyrev ⁽¹⁾ ⁽¹⁾ FSBI Research Institute of Medical Genetics, Tomsk, Russia ⁽²⁾ FSBI Research Institute of Complex Problems of Cardiovascular Diseases, Kemerovo, Russia MOLECULAR GENETICS PECULIARITIES OF FIBROGENESIS IN DIFFERENT PATHOLOGICAL TRAITS IN HUMANS	11-40:12-00
8	L. Bryzgalov, I. Brusentsov, T. Merkulova Institute of Cytology and Genetics SB RAS, Novosibirsk, Russian Federation A NOVEL APPROACH TO FUNCTIONAL SNP DISCOVERY FROM GENOME-WIDE DATA REVEALS NEW VARIANTS, ASSOCIATED WITH COLON CANCER RISK	12-00:12-20
9	V.V.Ilinsky ⁽¹⁾⁽²⁾, O.L. Kardymon ⁽²⁾ ⁽¹⁾ Vavilov Institute of General Genetics of RAS, Moscow, Russia ⁽²⁾ Genotek Inc., Moscow, Russia FETUS WHOLE GENOME SEQUENCE BY CELL-FREE DNA FROM MOTHER’S BLOOD	12-20:12-40
10	S. Sharapov ⁽¹⁾⁽²⁾, Y. Tsepilov ⁽¹⁾⁽²⁾, J. Ried ⁽³⁾, K. Strauch ⁽³⁾⁽⁴⁾, C. Gieger ⁽³⁾, Y. Aulchenko ⁽¹⁾ ⁽¹⁾ Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia ⁽²⁾ Novosibirsk State University, Novosibirsk, Russia ⁽³⁾ Institute of Genetic Epidemiology, Helmholtz Zentrum München – German Research Center for Environmental Health, Neuherberg, Germany ⁽⁴⁾ Institute of Medical Informatics, Biometry and Epidemiology, Chair of Genetic Epidemiology, Ludwig-Maximilians-Universität, Munich, Germany GENOME-WIDE ENVIRONMENTAL SENSITIVITY ANALYSIS OF HUMAN METABOLOMICS DATA	12-40:13-00
Lunch 13-00:14-00
11	V. Maksimov Federal State Budgetary Institution of Internal and Preventive Medicine Siberian Branch under the Russian Academy of Medical Sciences, Novosibirsk, Russia PERSONALIZED GENOMIC MEDICINE: TODAY AND PROSPECTS	14-00:14-30
12	M. Golubenko, R. Salakhov, O. Makeeva, V. Kashtalap, O. Barbarash, V. Puzyrev Institute of Complex Problems of Cardiovascular Diseases, Kemerovo, Russia ANALYSIS OF MITOCHONDRIAL DNA POLYMORPHISM IN PATIENTS WITH ACUTE CORONARY SYNDROME	14-30:14-50
13	E. Trifonova ⁽¹⁾, N. Ershov ⁽²⁾, V. Serebrova ⁽¹⁾, V. Stepanov ⁽¹⁾ ⁽¹⁾ Institute for medical genetics SB RAМS, Tomsk, Russia ⁽²⁾ Institute of cytology and Genetics SB RAS, Novosibirsk, Russia INTEGRATIVE TRANSCRIPTOME-BASED APPROACH FOR ASSOCIATION STUDIES: IDENTIFICATION OF NEW GENETIC MARKERS FOR PREECLAMPSIA	14-50:15-10
14	S. Lenskiy, Y. Lenskaya Ural Federal University, Ekaterinburg, Russia RELATIONSHIPS BETWEEN HUMAN GENE SET AND SET OF GENE DISORDERS	15-10:15-30
15	E. Bragina ⁽¹⁾, M. Freidin ⁽¹⁾, E. Tiys ⁽²⁾, L. Koneva ⁽¹⁾, V. Ivanisenko ⁽²⁾, V. Puzyrev ⁽¹⁾ ⁽¹⁾ Institute of Medical Genetics, Siberian Branch of Russian Academy of Medical Sciences, Tomsk, Russia ⁽²⁾ Institute of Cytology and Genetics, Siberian Branch of Russian Academy of Science, Novosibirsk, Russia GENOME-PHENOME RELATIONSHIPS OF POLAR IMMUNOLOGICAL DISEASES	15-30:15-50
*Coffee /tea break 16-50:16-00*
16	V. Kharkov, O. Radzhabov, V. Stepanov FSBI Research Institute of Medical Genetics, Tomsk, Russia GENE POOL OF THE NATIVE POPULATIONS OF DAGESTAN: TERRITORIAL SUBDIVISION AND CORRELATION WITH LINGUISTIC CLASSIFICATION FROM THE DATA OF Y-CHROMOSOME MARKERS	16-00:16-20
17	O. Posukh ⁽¹⁾⁽²⁾, A. Сhurbanov ⁽³⁾, T. Karafet ⁽³⁾, A. Bondar ⁽⁴⁾, I. Morozov ⁽²⁾⁽⁴⁾, V. Mikhalskaya ⁽¹⁾⁽²⁾, M. Zytsar ⁽¹⁾⁽²⁾ ⁽¹⁾ Institute of Cytology and Genetics, Novosibirsk, Russia; ⁽²⁾ Novosibirsk State University, Novosibirsk, Russia; ⁽³⁾ ARL Division of Biotechnology, University of Arizona, Tucson, Arizona, USA; ⁽⁴⁾ Institute of Chemical Biology and Fundamental Medicine, Novosibirsk, Russia WHOLE EXOME SEQUENCING IN ALTAIAN FAMILIES (THE ALTAI REPUBLIC, SOUTHERN SIBERIA) WITH CONGENITAL HEARING LOSS	16-20:16-40
18	M. Ponomarenko ⁽¹⁾, O. Arkova ⁽¹⁾, O. Saik ⁽¹⁾, T. Arshinova ⁽¹⁾, P. Ponomarenko ⁽²⁾, D. Rasskazov ⁽¹⁾, M. Genaev ⁽¹⁾, E.G Komyshev ⁽¹⁾⁽³⁾, L. Savinkova ⁽¹⁾, N.A. Kolchanov ⁽¹⁾⁽³⁾ ⁽¹⁾ Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia ⁽²⁾ Children’s Hospital Los Angeles, Los Angeles, CA 90027, USA ⁽³⁾ Novosibirsk State University, Novosibirsk, Russia ANNOTATIONS IN SILICO OF 388 SNPS OF THE CORE-PROMOTERS OF 68 HUMAN FEEDING BEHAVIOR GENES IN TERMS OF THEIR POTENTIAL ASSOCIATIONS WITH NERVOUS DISORDERS	16-40:17-00
19	G.I. Lifshits Institute of Chemical Biology and Fundamental Medicine Siberian Branch of the Russian Academy of Sciences TRANSLATIONAL RESEARCH OF PHARMACOGENETIC TECHNOLOGIES IN THE TREATMENT OF CARDIOVASCULAR DISEASES	17-00:17-20
20	Rene te Boekhorst, Sylvia Beka, Irina Abnizova Bio-computation Group, School of Computer Science, University of Hertfordshire, UK CHARACTERISTICS OF TYPE 1 DIABETES SUSCEPTIBILITY REGIONS	17-20:17-40

June 25, Wednesday The Exhibition Center of the SB RAS

Morning Session
9:00-13:00

MICROSYMPOSIUM “TRANSLATIONAL MEDICINE”

Co-chairpersons:
Prof. Mikhail Moshkin, Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
Prof. Yoichiro Iwakura, Center for Animal Disease Models, Research Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, Japan

TRANSLATIONAL MEDICINE
No	Author(s) and Title of Talk	Timeline
	M.P. Moshkin, Institute of Cytology and Genetics, Siberian Branch of the Russian Academy of Sciences, Russia Opening remark	9:00-9:10
1	Y. Iwakura Tokyo University of Science, Tokyo, Japan THE ROLE OF DECTIN-1 AND DECTIN-2 IN THE HOST DEFENSE AGAINIST FUNGI AND IN INTESTINAL IMMUNITY KEYNOTE TALK	9:10-10:00
2	M.Y. Pakharukova ⁽¹⁾, N.I. Ershov ⁽¹⁾, D.S. Pirozhkova ⁽¹⁾, V. A. Vavilin ⁽²⁾, K.S. Zadesenets ⁽¹⁾, T.G. Duzhak ⁽³⁾, V.A. Mordvinov ⁽¹⁾ ⁽¹⁾ Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia ⁽²⁾ Institute of Molecular Biology and Biophysics SB RAMS, Novosibirsk, Russia ⁽³⁾ International Tomography Center SB RAS, Novosibirsk, Russia MOLECULAR MECHANISMS OF METABOLISM, EXCRETION AND DRUG TOLERANCE IN HUMAN LIVER FLUKE OPISTHORCHIS FELINEUS	10:00-10:20
3	E. Kozhevnikova Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia GUT MUCOSAL PROTEOGLYCAN MUCIN2 COMPROMISES ANIMAL SEXUAL BEHAVIOR	10:20-10:40
4	P.N. Menshanov, A.E. Akulov, N.N. Dygalo Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia HIPPOCAMPAL NEUROCHEMICAL PROFILE IN NEONATAL RATS: EFFECTS OF ANESTHESIA	10:40-11:00
Coffee/tea break 11:00-11:20
5	S.P. Medvedev Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia THE USE OF NEW GENOME ENGINEERING TECHNOLOGIES FOR CREATION OF ISOGENIC AMYOTROPHIC LATERAL SCLEROSIS CELL MODEL	11:20-11:40
6	A.A. Nemudryi Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia RESCUE OF BRATTLEBORO RAT STRAIN MUTANT PHENOTYPE USING TALEN AND CRISPR/Cas9 SYSTEMS	11:40-12:00
7	N.A. Stefanova, N.A. Muraleva, A.A. Strunov, E.V. Kiseleva, N.G. Kolosova Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia THE SENESCENCE-ACCELERATED OXYS RATS AS A MODEL OF ALZHEIMER DISEASE	12:00-12:20
8	M.L. Perepechaeva ⁽¹⁾, N.G. Kolosova ⁽²⁾, A.Yu. Grishanova ⁽¹⁾ ⁽¹⁾ Institute of Molecular Biology and Biophysics of SB RAMS, Novosibirsk, Russia ⁽²⁾ Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia AhR-DEPENDENT GENES CYP1B1 AND CYP2J3 ARE INVOLVE IN CARDIOVASCULAR PATHOLOGY OF SENESCENCE-ACCELERATED OXYS RATS	12:20-12:40
9	A.B. Salmina, N.A. Malinovskaya, O.L. Lopatina, Y.K. Khomleva Krasnoyarsk State Medical University named after Professor V.F. Voino-Yasenetsky, Krasnoyarsk, Russia MOLECULAR MARKERS AND TARGETS FOR DIAGNOSTICS AND TREATMENT OF NEURODEGENERATION AND NEURODEVELOPMENTAL DISORDERS	12:40-13:00
Lunch 13:00-14:00

June 25, Wednesday THE MUSIC HALL OF THE SB RAS

Evening session
14:00-18:00

MICROSYMPOSIUM “TRANSLATIONAL MEDICINE”

Co-chairpersons:
Prof. Mikhail Moshkin, Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
Prof. Steven A. Brown, Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland

TRANSLATIONAL MEDICINE
No	Author(s) and Title of Talk	Timeline
1	S.A. Brown Institute of Pharmacology and Toxicology, University of Zurich, Zurich, Switzerland MECHANISMS OF CIRCADIAN PLASTICITY KEYNOTE TALK	14:00-14:40
2	A. Baranova ⁽¹⁾⁽²⁾, L.Wang ⁽¹⁾, T. Cui ⁽¹⁾, B.Veytsman ⁽¹⁾, S.Bruskin ⁽³⁾ ⁽¹⁾ School of Systems Biology, George Mason University, Fairfax, VA, USA ⁽²⁾ Research Centre for Medical Genetics RAMS, Moscow, Russia ⁽³⁾ Vavilov Institute of General Genetics RAS, Moscow, Russia ATTRACTOR BASED CLASSIFIERS FOR PREDICTION OF POST-TREATMENT SURVIVAL IN CANCER AND DETECTION OF NON-MALIGNANT DISEASES	14:40-15:00
3	O.E. Redina, S.E. Smolenskaya, T.O. Abramova, L.N. Ivanova, A.L. Markel Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia GENETIC DISSECTION OF INHERITED HYPERTENSIVE STATE IN ISIAH RATS USING KIDNEY GENE-EXPRESSION AND GENOME MAPPING	15:00-15:20
4	E. Pozhilenkova Krasnoyarsk State Medical University named after Professor V.F.Voino-Yasenetsky, Krasnoyarsk, Russia DEVELOPMENT OF CELLULAR MODELS FOR TRANSLATIONAL RESEARCH IN NEUROPHARMACOLOGY	15:20-15:40
Coffee/tea break 15:40-16:00
5	I L. Erokhin National Biotechnological Company, LLC, Moscow, Russia ONCOGENESIS MODEL BASED ON THE GENOME STRUCTURE OF MULTICELLULAR ORGANISMS	16:00-16:20
6	D.V. Telegina, O.S. Kozhevnikova, S.I. Baiborodin, N.G. Kolosova Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia ALTERATIONS OF RAT RETINAL PIGMENT EPITHELIUM WITH AGE AND AMD-LIKE RETINOPATHY	16:20-16:40
7	B. Veytsman, T.Cui, L. Wang, A. Baranova School of Systems Biology, George Mason University, Fairfax, VA, USA SYSTEMIC SHIFTS IN MICRO RNA LANDSCAPE AS A DIAGNOSTIC AND PREDICTION TOOL	16:40-17:00
8	L.N. Grinkevich I.P. Pavlov Institute of Physiology of RAS, St. Petersburg, Russia EPIGENETIC MECHANISMS OF MEMORY FORMATION: THE ROLE OF THE HISTONE ACETYLATION AND METHYLATION IN AVERSIVE LEARNING	17:00-17:20
Discussion 17:20-18:00

AUDITORIUM NEAR CONFERENCE HALL
IN THE EXHIBITION CENTRE SB RAS

POSTER SESSION OF INTERNATIONAL SYMPOSIUM
“HUMAN GENETICS”
17-40:19-00

SECTION MEDICAL GENETICS
POSTER SESSION

K.S. Astrakova, E.V. Shakhtshneider, Y.I Ragino, A.M. Chernjavski, E.V. Kashtanova, Y.V. Polonskaya, M.I. Voevoda
Federal State Budgetary Institution of Internal and Preventive Medicine Siberian Branch under the Russian Academy of Medical Sciences, Novosibirsk, Russia
CHOLESTEROL ESTER TRANSFER PROTEIN GENE POLYMORPHISM IN MEN WITH CORONARY ATHEROSCLEROSIS

N.P. Babushkina ⁽¹⁾, A.F. Garaeva ⁽¹⁾, E.Yu. Bragina ⁽¹⁾, A.N. Nogovitsina ⁽²⁾, A.A. Rudko ⁽¹⁾
⁽¹⁾ – Research Institute of Medical Genetics SB RAMS, Tomsk, Russia
⁽²⁾ – Yakutsk Scientific Centre of Complex Medical Problems SB RAMS, Yakutsk, Russia
STUDYING OF GENES REGULATING IMMUNE RESPONSE AT PULMONARY TUBERCULOSIS IN YAKUTS

G. Eslami ⁽¹⁾, B. Hajimohammadi ⁽²⁾, M. Gholamrezaei ⁽¹⁾, S. Khalatbary ⁽²⁾, A. Zohortabar ⁽²⁾, M. Ardian ⁽³⁾
⁽¹⁾ – Department of Parasitology and Mycology, Faculty of Medicine, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
⁽²⁾ – Department of Food Hygiene and Safety, Faculty of Health, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
⁽³⁾ – Technical officer of health for slaughterhouse in Yazd, Iran
PRACTICAL APPROACH FOR DNA EXTRACTION OF LINGUATULA SERRATA NYMPHS: AN ANALYTICAL METHOD

A.F. Garaeva, A.A. Rudko, E.Yu. Bragina, N.P. Babushkina, M.B. Freidin
Research Institute of Medical Genetics SB RAMS, Tomsk, Russia
STUDY OF GENES CAUSING ATYPICAL FAMILIAL MYCOBACTERIOSIS IN TOMSK TUBERCULOSIS PATIENTS

B.O. Ibeh
Emerging Health and Environment Initiative, Abuja, Nigeria
CCR5 AND CXCR4 CORECEPTOR PROFILE IN RESISTANCE HIV EXPOSED BUT SERONEGATIVE INDIVIDUALS OF NIGERIAN ORIGIN

D.E. Ivanoshchuk ⁽¹⁾⁽²⁾, N.A. Konovalova ⁽³⁾, I.Y. Bychkov ⁽⁴⁾, O.S. Konovalova ⁽³⁾, A.V. Eremina ⁽⁴⁾, M.N. Ponomareva ⁽⁵⁾, M.I. Voevoda ⁽¹⁾⁽²⁾, A.G. Romaschenko ⁽¹⁾
⁽¹⁾ – Institute of Cytology and Genetics, Siberian Branch, Russian Academy of Sciences, Novosibirsk, Russia
⁽²⁾ – Federal State Budgetary Institution of Internal and Preventive Medicine , Siberian Branch, Russian Academy of Medical Science, Novosibirsk, Russia
⁽³⁾ – Tyumen State Medical Academy, The Ministry of Health of the Russian Federation, Tyumen, Russia
⁽⁴⁾ – The Academician S.N. Fyodorov FSBI IRTC “Eye Microsurgery” of Ministry of Health of RF, Novosibirsk branch, Novosibirsk, Russia
⁽⁵⁾ – The Kurgan Regional Hospital for War Veterans, Kurgan, Russia
POSSIBLE ASSOCIATION BETWEEN THE TRPV1 GENE RS222747 POLYMORPHISM AND PRIMARY OPEN ANGLE GLAUCOMA IN WESTERN SIBERIA PATIENTS

A.A. Ivanova ⁽¹⁾, V.N. Maksimov ⁽¹⁾⁽⁴⁾, P.S. Orlov ⁽¹⁾⁽²⁾, D.E. Ivanoshchuk ⁽¹⁾⁽²⁾, S.V. Savchenko ⁽³⁾⁽⁴⁾, M.I. Voevoda ⁽¹⁾⁽²⁾
⁽¹⁾ – Federal State Budgetary Institution of Internal and Preventive Medicine Siberian Branch under the Russian Academy of Medical Sciences, B. Bogatkova st., 175/1, Novosibirsk, 630089 Russia
⁽²⁾ – Institute of Cytology and Genetics, Siberian Branch under the Russian Academy of Sciences, Novosibirsk, Russia
⁽³⁾ – Novosibirsk Regional Office of Forensic Medical Examination, Novosibirsk, Russia
⁽⁴⁾ – Novosibirsk State Medical University, Novosibirsk, Russia
ASSOCIATION OF THE GENETIC MARKERS FOR MYOCARDIAL INFARCTION WITH SUDDEN CARDIAC DEATH IN A RUSSIAN POPULATION

L.A Koneva ⁽¹⁾⁽²⁾, M. B. Freidin ⁽¹⁾, E.Yu. Bragina ⁽¹⁾, V.P Puzyrev ⁽¹⁾, R.C McEachin ⁽²⁾
⁽¹⁾ – Research Institute of Medical Genetics SB RAMS, Tomsk, Russia
⁽²⁾ – Center for Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI, USA
MODELING GENETIC INFLUENCES ON TWO DISEASES THAT ARE UNUSUALLY RARE IN CO-OCCURRENCE_ BRONCHIAL ASTHMA AND PULMONARY TUBERCULOSIS

E.E. Korbolina, N.I. Ershov, L.O. Bryzgalov, O.S. Kozhevnikova, N.G. Kolosova
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
CONGENIC STRAINS FOR STUDYING ACCELERATED SENESCENCE IN OXYS RATS_ RETINAL TRANSCRIPTOME AND CANDIDATE GENE ANALYSIS BY RNASEQ

N.L. Podkolodnyy ^(1)(3)(4), D.A. Afonnikov ⁽¹⁾, Yu.Yu. Vaskin ⁽²⁾, L.O. Bryzgalov ⁽¹⁾, V.A. Ivanisenko ⁽¹⁾, P.S. Demenkov ⁽¹⁾, M.P. Ponomarenko ⁽¹⁾, D.A. Rasskazov ⁽¹⁾, K.V. Gunbin ⁽¹⁾, I. Protsyuk ⁽²⁾, I. Shutov ⁽²⁾, P. Leontyev ⁽²⁾, M.Yu. Fursov ⁽²⁾, N.P. Bondar ⁽¹⁾, E.V. Antontseva ⁽¹⁾, T.I. Merkulova ⁽¹⁾, N.A. Kolchanov ⁽¹⁾⁽⁴⁾
⁽¹⁾ – Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia;
⁽²⁾ – Ltd. Novosibirsk Center of Information Technologies “UNIPRO”, Novosibirsk, Russia;
⁽³⁾ – Institute of Computational Mathematics and Mathematical Geophysics, SB RAS, Novosibirsk, Russia;
⁽⁴⁾ – Novosibirsk State University, Novosibirsk, Russia.
THE SNP-MED SYSTEM FOR PERSONAL MEDICINE_ ANALYZE THE EFFECT SNP TO THE FUNCTION OF GENES ASSOCIATED WITH DISEASES

R.S. Sergeev, I.S. Kavaliou, A.V. Tuzikov
United Institute of Informatics Problems NASB, Minsk, Belarus
MUTATION ANALYSIS OF MYCOBACTERIUM TUBERCULOSIS GENOME AND ASSOCIATION WITH DRUG RESISTANCE

S.O. Vechkapova
Design Technological Institute of Digital Techniques of SB RAS, Novosibirsk, Russia
INTERMOLECULAR INTERACTIONS IN THE IONOTROPIC GLUTAMATE RECEPTOR SUPRAMOLECULAR COMPLEXES IN THE PROCESSES OF NEURONAL SYNAPTIC PLASTICITY

E.N. Voropaeva, T.I. Pospelova, M.I. Voevoda, V.N. Maximov
Institute of Therapy and Preventive Medicine SB RAMS, State Medical University, Novosibirsk, Russia
POLYMORPHISM RS1625895 GENE TP53 AND EFFECTIVENESS OF TREATMENT OF DLBCL

SECTION TRANSLATIONAL MEDICINE
POSTER SESSION

A.V. Avetisyan ⁽¹⁾, R.A. Simonyan ⁽¹⁾, I.Ju Aleksandrova ⁽²⁾, A.N. Samokhin ⁽²⁾, N.V. Bobkova ⁽²⁾
⁽¹⁾ – A.N.Belozersky Institute of Physico-Chemical Biology, Moscow State University, Russia;
⁽²⁾ – Institute of Cell Biophysics RAN, Moscow Region, Pushchino, Russia
MITOCHONDRIAL DYSFUNCTIONS IN ANIMAL MODEL OF SPORADIC ALZHEIMER’S DISEASE

N.P. Bondar, L.O. Bryzgalov, N.I. Ershov, M.Yu. Matveeva
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
THE USE OF 3D-CHROMATIN STRUCTURE DATA TO PREDICT NOVEL GENES ASSOCIATED WITH THE DEVELOPMENT OF DEPRESSION.

A.G. Galyamina, I.L. Kovalenko, N. N. Kudryavtseva
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
RELATIONSHIP BETWEEN ANXIETY AND DEPRESSION IN THE CHRONIC SOCIAL DEFEAT STRESS MODEL: PHARMACOLOGICAL RESEARCH

E.V. Ignatieva
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
THE COMPELLATION OF HUMAN GENES CONTROLLING FEEDING BEHAVIOR OR ASSOCIATED WITH BODY MASS INDEX AND ITS FUNCTIONAL AND GENOMIC CHARACTERISTICS

I.L. Kovalenko1, A.G. Galyamina1, D.A. Smagin1, 2, T.V. Michurina2,3, G. Enikolopov 2,3, N.N. Kudryavtseva1
⁽¹⁾ – Institute of Cytology and Genetics SD RAS, Novosibirsk, Russia,
⁽²⁾ – NBIC, Moscow Institute of Physics and Technology, Moscow, Russia,
⁽³⁾ – Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
IMPLICATIONS OF HOSTILE ENVIRONMENT AND SOCIAL INSTABILITY IN ADOLESCENT MICE

O.S. Kozhevnikova, E.E. Korbolina, N.I. Ershov, N.G. Kolosova
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
AGING OF RAT RETINA: TRANSCRIPTOME STUDY

I.V. Medvedev ⁽¹⁾, A.M. Spitsina ⁽²⁾, O.V. Vishnevsky ⁽¹⁾, N.S. Safronova ⁽¹⁾⁽²⁾, Efimov V.M. ⁽¹⁾, Y.L. Orlov ⁽¹⁾⁽²⁾
⁽¹⁾ – Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
⁽²⁾ – Nosobirsk State University, Novosibirsk, Russia
COMPUTER ANALYSIS OF HUMAN GENE EXPRESSION DATA IN BRAIN USING MICROARRAYS

N. Muraleva, O. Kozhevnikova, E. Korbolina, A. Fursova, N. Kolosova
Institute of Cytology and Genetics, Novosibirsk, Russia
ESTIMATION OF IMPACT OF ALPHA-CRYSTALLIN’S ALTERATIONS ON THE DEVELOPMENT OF AMD-LIKE RETINOPATHY IN OXYS RATS

E.A. Rudnitskaya ⁽¹⁾, K.Y. Maksimova ⁽²⁾, N.A. Stefanova ⁽¹⁾
⁽¹⁾ – Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
⁽²⁾ – Siberian State Medical University, Tomsk, Russia
MELATONIN IN PREVENTION OF ALZHEIMER’S DISEASE-LIKE PATHOLOGY IN OXYS RATS

D. Salyakina, N.F. Tsinoremas
Center for Computational Science, University of Miami, Miami, USA
VIRAL EXPRESSION ASSOCIATED WITH GASTROINTESTINAL ADENOCARCINOMAS IN TCGA HIGH-THROUGHPUT SEQUENCING DATA

Y.N. Shvarev ⁽¹⁾⁽²⁾, P.S. Demenkov ⁽²⁾⁽³⁾, O.M. Balakireva ⁽²⁾, V.A. Ivanisenko ⁽²⁾, N.A. Kolchanov ⁽²⁾
⁽¹⁾ – Neonatal research Unit, Department of Woman & Child Health, Astrid Lindgren Children’s Hospital, Karolinska Institutet, Stockholm, Sweden.
⁽²⁾ – Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia.
⁽³⁾ – Novosibirsk State University, Novosibirsk, Russia.
CAN OPIOID AND SUBSTANCE P SYSTEM INTERACTION ANTOGONIZE MORPHINE-INDUCED RESPIRATORY DEPRESSION?

D.A.Smagin ⁽¹⁾⁽²⁾, N.N. Kudryavtseva ⁽¹⁾, G.N. Enikolopov ⁽²⁾⁽³⁾
⁽¹⁾ – Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
⁽²⁾ – NBIC, Moscow Institute of Physics and Technology, Moscow, Russia
⁽³⁾ – Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA
ACTIVATION OF HIPPOCAMPAL CELL PROLIFERATION AND DECREASE OF C-FOS EXPRESSION IN THE AMYGDALA UNDER POSITIVE FIGHTING EXPERIENCE IN MALE MICE

A.O. Vitovtov, N.A. Muraleva, N.A. Stefanova, N.G. Kolosova
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
CONSERVATIVE mTOR SIGNALING PATHWAY AS A TARGET FOR PROPHYLAXIS OF ACCELERATED BRAIN AGING