{"id":811,"date":"2021-10-02T08:32:11","date_gmt":"2021-10-02T05:32:11","guid":{"rendered":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/?p=811"},"modified":"2021-10-02T08:33:02","modified_gmt":"2021-10-02T05:33:02","slug":"changes-in-the-size-of-cell-nuclei-in-response-to-smc-proteins-degradation-in-mammalian-cells","status":"publish","type":"post","link":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/2021\/10\/02\/changes-in-the-size-of-cell-nuclei-in-response-to-smc-proteins-degradation-in-mammalian-cells\/","title":{"rendered":"Changes in the size of cell nuclei in response to SMC proteins degradation in mammalian cells"},"content":{"rendered":"<p>Myakinkov Ivan Olegovich; Khabarova Anna Aleksandrovna; Yunusova Anastasia Maratovna; Battulin Nariman Rashitovich<\/p>\n<p>Novosibirsk State University, Novosibirsk, Russia; Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia<\/p>\n<p>SMC complexes condensin and cohesin are essential for the three-dimensional organization of genome and cell division. However, a lot about their function remains unknown. We apply a proteasomal degradation approach to these complexes in order to examine the knockout phenotype in cell cultures. During these experiments, we have noticed a notable enlargement of the cell nuclei. We decided to inspect this phenomenon.<\/p>\n<p>&nbsp;<\/p>\n<a href=\"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-content\/uploads\/sites\/40\/2021\/10\/Myakinkov-I_Poster.pdf\" class=\"pdfemb-viewer\" style=\"\" data-width=\"max\" data-height=\"max\"  data-toolbar=\"bottom\" data-toolbar-fixed=\"off\">Myakinkov-I_Poster<br\/><\/a>\n","protected":false},"excerpt":{"rendered":"<p>Myakinkov Ivan Olegovich; Khabarova Anna Aleksandrovna; Yunusova Anastasia Maratovna; Battulin Nariman Rashitovich Novosibirsk State University, Novosibirsk, Russia; Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia SMC complexes condensin and cohesin are essential for the three-dimensional organization of genome and &hellip; <a href=\"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/2021\/10\/02\/changes-in-the-size-of-cell-nuclei-in-response-to-smc-proteins-degradation-in-mammalian-cells\/\">Continue reading <span class=\"meta-nav\">&rarr;<\/span><\/a><\/p>\n","protected":false},"author":59,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":[],"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/posts\/811"}],"collection":[{"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/users\/59"}],"replies":[{"embeddable":true,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/comments?post=811"}],"version-history":[{"count":1,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/posts\/811\/revisions"}],"predecessor-version":[{"id":813,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/posts\/811\/revisions\/813"}],"wp:attachment":[{"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/media?parent=811"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/categories?post=811"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/conf.icgbio.ru\/sbb-plantgen-2021\/wp-json\/wp\/v2\/tags?post=811"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}