ПРОГРАММА

PROGRAM
of the 10th International Young Scientists School

«Systems Biology and Bioinformatics», SBB’2018

27-31 August 2018, Novosibirsk, Akademgorodok

 

27 August, Monday (The Conference Hall, ICG SB RAS)

08:30-9:30 Registration

9:30-9:35 Opening ceremony

N.A. Kolchanov, Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia

9:35-10:20 Systems Biology of Cell Cycle ControlBarberis Matteo, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam

10:20-11:05 Phylogenetic footprinting with intra-motif dependencies,  Ivo Grosse, Halle-Wittenberg University, Halle; Novosibirsk State University, Novosibirsk, Russia; German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Germany

11:05-11:20 Coffee-break

11:20-12:05 Genetics of human diseases and Rational Drug Design, Peter Vlasov, Institute of Science and Technology, Austria

12:05-12:50 FAIR (Findable, Accessible, Interoperable, and Reusable) research data principles explained, Olga Krebs, Heidelberg Institute for Theoretical Studies

Metabolic Control Analysis, Hans Westerhoff, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam

12:50-14:00 Lunch

14:00-14:45 Homology modeling of proteins, Anastasia Bakullina, Novosibirsk State University, Russia, Novosibirsk

14:45-15:30 Stoichiometric models of metabolic networks, M. Zakhartsev, Hohenheim University, Stuttgart, Germany

15:30-16:15 FAIR (Findable, Accessible, Interoperable, and Reusable) research data principles explained, Olga Krebs, Heidelberg Institute for Theoretical Studies

16:15-16:30 Coffee-break

16:30-17:15 Digital Infrared Thermography as a State-of-the-Art Technology in Biomedicine, B. G. Vainer, Rzhanov Institute of Semiconductor Physics SB RAS, Novosibirsk, Russia

17:15-18:00 The Genomic Basis of Human Lifespan, Joshi Peter, University of Edinburgh, Edinburgh

18:00-18:45 Dynamic networks dealing with oxidative stress: From data and design principles to personalised therapies, Alexey Kolodkin, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam

18:45-19:15 Round table “Fulbright”

19:15-21:00 Welcome party

28 August, Tuesday (The Conference Hall, ICG SB RAS)

09:00-11:00 Practical workshops 1

11:00-11:20 Coffee-break

11:20-13:00 Practical workshops 1

13:00-14.00 Lunch

14:00-16:00 Practical workshops 1

16.00-16.20 Coffee-break

16.30-18.00 Practical workshops 1

29 August, Wednesday

09:00-11:00 Practical workshops 2

11:00-11:20 Coffee-break

11:20-13:00 Practical workshops 2

13:00-14.00 Lunch

14:00-16:00 Practical workshops 2

16.00-16.20 Coffee-break

16.30-18.00 Practical workshops 2

30 August, Thursday

9:00-11:00 Participants presentations

11:00-11:30 Coffee-break

11:30-13.00 Participants presentations

13:00-14:00 Lunch

14:00-15:00 Lunch

15:00-16:00 Participants presentations

16.00-16.30 Coffee-break

16.30-18.30 Participants presentations

31st August, Thursday

9:00-11:00 Participants presentations

11:00-11:30 Coffee-break

11:30-13.00 Participants presentations

13:00-14:00 Lunch

14:00-16:00 Participants presentations

16.00-16.30 Coffee-break

16.30-17.30 Participants presentations

17.30–18.00 Closing ceremony, awards for the best young scientists reports.

PRACTICAL WORKSHOPS 1 (August, 28):

Barberis Matteo, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam Modeling cell cycle control
Zakhartsev Maksim, Norwegian University of Life Sciences, Ås
Olga Krebs, Heidelberg Institute for Theoretical Studies, German
Topological analysis of the stoichiometric models of metabolic networks
Alexey Kolodkin, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, Holland
Olga Krebs, Heidelberg Institute for Theoretical Studies, German
Systems biology and computer modeling in personalized medicine
Anastasia Bakulina, Novosibirsk State University, Novosibirsk, Russia Homology modeling of proteins
Peter Vlasov, Institute of Science and Technology, Austria (two days) Genetics of human diseases and Rational  Drug Design
Elena Zemlyanskaya and Ivo Grosse

Institute of Cytology and Genetics of the Russian Academy of Sciences, Novosibirsk, Russia; Institute of Computer Science at Martin Luther University Halle-Wittenberg, Germany; German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig, Germany

Multiple hypothesis testing in big data analytics and the life sciences

 

PRACTICAL WORKSHOPS 2 (August, 29):

Zakhartsev Maksim, Norwegian University of Life Sciences, Ås
Olga Krebs, Heidelberg Institute for Theoretical Studies, German
Topological analysis of the stoichiometric models of metabolic networks
Saik Olga, Institute of Cytology and Genetics of SB RAS, Novosibirsk State University, Novosibirsk, Russia Application of ANDSystem for the reconstruction and analysis of molecular-genetics networks, associated with diseases and phenotypic traits
Boris Vainer, Rzhanov Institute of Semiconductor Physics  SB RAS, Novosibirsk, Russia The excursion to Rzhanov Institute of Semiconductor Physics with practical studying of the thermal imaging method
Anastasia Bakulina, Novosibirsk State University, Novosibirsk, Russia Homology modeling of proteins
Peter Vlasov, Institute of Science and Technology, Austria (two days) Genetics of human diseases and Rational  Drug Design

YOUNG SCIENTISTS’ PRESENTATIONS (The Conference Hall, ICG SB RAS)

30st August, Thursday

9:00 — 9:15 Identification of Loci Determining Resistance of Spring Barley to Spot and Net Blotch, Using Association Mapping Approach\ I V. Bykova*, S.A.Gorobets, N. M. Lashina, V. M. Efimov, O. S. Afanasenko, E. K. Khlestkina
9:15 — 9:30 Search for single-nucleotide polymorphisms associated with accelerated senescence in OXYS rats\ V. Devyatkin, O. Redina, N. Muraleva
9:30 — 9:45 Design of genetic sensors to ethylene based on bioinformatics analysis of whole-genome data\ V. Dolgikh
9:45 — 10:00 Investigation of genetic polymorphism of Avena sativa varieties and Avena sterilis samples using SSR-markers\ N.I. Drobot
10:00 — 10:15 Early and late transcriptional responses to the low concentra-tion of salicylic acid in Arabidopsis thaliana L. root\ E. Elgaeva, E. Zemlyanskaya, D. Novikova, V. Mironova
10:15 — 10:30 The Hormonal Mechanism Of Heat Stress Effect On The Carbohydrate Metabolism In Drosophila Melanogaster Females\ M.A. Eremina, E.K. Karpova, N.E. Gruntenko
10:30 — 10:45 Phenotype characters statistical analysis for selection perspectives.\ T.V.*Erst1, V.K. Khlestkin1
10:45 — 11:00 Identification of genes, associated with black pigmentation of seeds in cereals, based on transcriptomic analysis\ Glagoleva A.Yu., Shmakov N.A., Shoeva O. Yu., Vasiliev G.V., Shatskaya N.V., Börner A., Afonnikov D.A., Khlestkina E.K.
11:00 — 11:30 Coffee-break
11:30 — 11:45 Ecotoxicity prediction of the new imidazole liquids with a phosphorus containing anion using QSAR\ N. Gogoleva, O. Bernachuk, A. Bernachuk
11:45 — 12:00 A database and analytical platform for mining billions of genetic associations\ D.D.Gorev, T.I.Shashkova, E.Pakhomov, A.Torgasheva, L.Klaric, A.Severinov, S.Sharapov, D.G. Alexeev Y.S.Aulchenko
12:00 — 12:15 Overexpression of Gclc in the Drosophila melanogaster thorax\ Z. Guvatova1, M. Shaposhnikov, E. Lashmanova, G. Krasnov, A. Kudryavtseva , A. Moskalev
12:15 — 12:30 Resistivity estimation for a row of potato starches of domestic collection\ L. Gvozdeva, V. Khlestkin
12:30 — 12:45 Computer Analysis of Genes Expression, Involved in the Serotonergic and Dopaminergic Systems Work, in the Ventral Tegmental Brain Area of Aggressive and Non-Agressive Rats

A.O. Bragin*, A.L. Markel, R.V. Kozhemyakina, Yu.L. Orlov

12:45 — 13:00 Study of the effect of nanocomposites based on humic substances of different nature on the causative agent of ring rot of Clavibacter michiganensis ssp. sepedonicus potato plants.\ O.A. Nozhkina, A. I. of Perfilyeva, I. A. of Graskova, B. G. Sukhov
13:00 — 14:00 Poster Session:

  • Heat shock response elements in the promoters of heat stress activated LTR retrotransposons in Macrostomum lignano \ V. Vavilova, E. Berezikov, K. Ustyantsev
  • Establishing free-living flatworm Macrostomum lignano as a model to study links between regeneration and cancer\ M. Biryukov, I. Sukhikh, V. Vavilova, K. Ustyantsev, E. Berezikov
  • Genomic variation in Austrian and Leningrad populations of snail Arianta arbustorum L.\ O. Bondareva, A. Kasianov and N. Abramson
  • The GAME Genes as a Target for de novo Domestication of Wild Potato

S.V. Gerasimova1,*, K.A. Ivanova1, E.K. Khlestkina1,2

  • Founder Effect in Prevalence of Hereditary Hearing Loss in Indigenous Siberian Populations \ V. Danilchenko 1,2*, M. Zytsar 1,2, O. Posukh 1,2
  • Hepatoprotective effect of various antioxidants in the pathogenesis of opisthorchiasis \ O. Zaparina1*, A. Kovner1, A. Rakhmetova2, M.Pakharukova1,2, V. Mordvinov1
  • Genetic diversity of facultative bread wheat from the VIR collection \\ A.V. Dementiev*, E.K.Potokina, O.P.Mitrofanova
  • The study of protein composition of Triaenophorus sp. at different stages of the life cycle and in different body segments\ A. Kochneva, E. Borvinskaya, D. Bedulina
14:00 — 15:00 Lunch
15:00 — 15:15 Adaptation of the brain tumors classifier, constructed on the direct mass spectrometric profiling data, to MALDI mass spectrometry analysis\ D. Ivanov, A. Sorokin, E. Zhvansky, V. Shurkhay, S.Pekov, I.Popov, E.Nikolaev
15:15 — 15:30 A STUDY OF MICROBIAL SPECTRA OF SOILS POTENTIALLY RELEVANT FOR THE FORMATION OF STABLE SOIL FOCI OF ANTHRAX\ Kalinin A. V., Tsygankova O. I., Koteneva E. A., Abramovich A. V., Pechkovsky G. A.
15:30 — 15:45 Differences in Association of the Genes with Cognitive Function and Symptom Severity of Belarusian Schizophrenia Patients\ H. Kandratsenkan, A. Nestsiarovich, I. Goloenko, N. Danilenko, A. Makarevich, V. Obyedkov, O. Davydenko
15:45 — 16:00 Human blood proteins and correlations with biochemical parameters after long duration space flights\ D.N. Kashirina, L.Kh. Pastushkova, A.M. Nosovsky, A.J. Percy, K.S. Kireev, C.H. Borchers, E.N. Nikolaev, I.M. Larina
16:00 — 16:30 Coffee-break
16:30 — 16:45 The variability of the amylose / amylopectin ratio and the preparative yield of S. tuberosum tuber starch\ Y. Khoroshavin1, 2 *, V. Khlestkin1, 2
16:45 — 17:00 Computer analysis of transcriptomes in glioma cells\ S.S. Kovalev, N.V. Gubanova, A.V. Tsukanov, A.O. Bragin, Y.L. Orlov
17:00 — 17:15 Genome-scale modeling of carbon assimilation in Geobacillus icigianus\ M.Kulyashov, I.Akberdin,A.Rozanov, S. Peltek
17:15 — 17:30 KINKS OF PLASMID PBR322 L.V. Yakushevich, L.A. Krasnobaeva
17:30 — 17:45 NGS data processing method for the mixture of chloroplast and mitochondrial DNA of barley\ A. Makarevich, O. Pankratov, M. Sinyavskaya, N. Lukhanina, A.Shymkevich, A.Liaudansky, I. Goloenko, N. Danilenko, O. Davydenko
17:45- 18:00 Selfish elements drive mitochondrial and nuclear mammalian genome size in opposite directions\ A.A. Mikhailova, A.G. Mikhaylova, D. Knorre, I. Mazunin, A. Reymond, K. Gunbin, K. Popadin
18:00— 18:15 Transition transversion ratio in mtDNA is higher in long- versus short-lived mammalians: effects of ROS and replication? \ A. G. Mikhaylova, A. A. Mikhaylova, K. Ushakova, E. Tretyakov, A. Yurchenko, D. Knorre, I. Mazunin, A. Reymond, K. Gunbin, K. Popadin
18:15 — 18:30 Developing FoldGO, the tools for multifactorial functional enrichment analysis\ Mukhin A.M., Wiebe D.S., Grosse I., Lashin S.A., Mironova V.V.

31st August, Friday

9:00 — 9:15 Comparison of evolutionary rates of the regions and nucleotide substitutions in the Allium plastomes\ D.O. Omelchenko, A.A. Krinitsina, M.D. Logacheva, M.S. Belenikin, E.A. Konorov, S.V. Kuptsov, A.P. Seregin, A.S. Speranskaya
9:15 — 9:30 Physicochemical Properties of vlhA Promoters in Mycoplasma gallisepticum and Their Possible Regulatory Role\ M. Orlov, I. Garanina, A. Ryasik, E. Zykova, G. Fisunov, A. Sorokin
9:30 — 9:45 Meta-analysis Genomics and Interactomics Data of Relationship Between the Host and Bacillus Anthracis\ G.A. Pechkosvkii1, A.V. Abramovich
9:45 — 10:00 Transcriptomic comparative analysis of hippocampal tissue and primary cultures after hyaluronidase treatment \ V. Pershin, A. Balashova, E. Guryev, L. Kurbatov, M. Gainullin, I. Mukhina
10:00 — 10:15 Using molecular docking to find the inhibitor of bacterial cellulose synthesis\ I. Petrushin
10:15 — 10:30 HOW HAVE OUR CLOCKS EVOLVED? ADAPTIVE AND DEMOGRAPHIC HISTORY OF THE OUT-OF-AFRICAN DISPERSAL TOLD BY THE GENETIC MARKERS OF MORNING-EVENING PREFERENCE \ A.A. Putilov, V.B. Dorokhov, A.N. Puchkova, D.S. Sveshnikov, M.G. Poluektov, O.G. Donskaya, L.P. Zakharenko
10:30 — 10:45 HETEROGENEITY OF LINKAGE DISEQUILIBRIUM ACROSS HUMAN POPULATION AND ITS INFLUENCE ON STATISTICAL PROPERTIES OF THE CONDITIONAL AND JOINT MODELS FOR GENETIC ASSOCIATION TESTING \ A.V. Severinov, S.A. Slavskii, T.I. Shashkova, D.D. Gorev, D.G. Alexeev, G.A. Bazykin, Y.S. Aulchenko
10:45 — 11:00 The software and database for Vertebrate imperfect mtDNA repeats annotation.\ V.A. Shamanskiy, K.Yu. Popadin, K.V. Gunbin
11:00 — 11:30 Coffee-break
11:30 — 11:45 Identification of Biomarkers and Intervention Targets for Coronary Artery Disease Based on Results of Genome-Wide Association scans\ T.I. Shashkova, A.Torgasheva, D.D.Gorev, E.Pakhomov, L.Klaric, A.V. Severinov,  S. Sharapov,  Y.A.Tsepilov, D.G. Alexeev, J.F. Wilson, P. Joshi, Y.S.Aulchenko
11:45 — 12:00 Identifying parasite resistance genes in Solanum tuberosum by RNA-seq\ N. Shmakov, A. Egorova, A. Glagoleva, A. Kochetov, D. Afonnikov
12:00 — 12:15 The interplay of Piwi and heterochromatin proteins in transposable element silencing in the germline of Drosophila melanogaster\ Anastasia Stolyarenko, Toomas Leinsoo, Yuri Abramov, Mikhail Klenov
12:15 — 12:30 Regulatory genes of anthocyanins biosynthesis in the barley grain \ K.V. Strygina, E.K. Khlestkina
12:30 — 12:45 Bioinformatics Study of Genes Expression in Rat Brain Areas by RT-PCR and their Role in Behavior\ K.A. Tabanyuhov, I.V. Chadaeva, A.O. Bragin, Y.L. Orlov
12:45 — 13:00 Gene Expression of Egr1, Gabrd, Zic2 and Shank3 Related to Aggressive Behavior on Rat Model\ K.A. Tabanyuhov, I.V. Chadaeva, A.O. Bragin, R.V. Kozhemyakina, A.V. Tsukanov, Y.L. Orlov
13:00 — 14:00 Lunch
14:00 — 14:15 The reasons for mtDNA structural instability: evolutionary physico-chemical retrospective.\ V.N. Timonina, D.A. Knorre, K.Yu. Popadin, K.V. Gunbin
14:15 — 14:30 Overexpression of whiA in Mycoplasma gallisepticum\ E. Tsoy, D. Evsyutina, G. Fisunov
14:30 — 14:45 Bioinformatics Tools for 3D Chromosome Contacts Analysis\ A.V. Tsukanov, A.O. Bragin, O. Thierry, Y.L. Orlov
14:45 — 15:00 Meta-analysis of whole-transcriptome data suggests new mechanisms of auxin-induced ethylene biosynthesis and sig-naling in Arabidopsis thaliana\ E. Ubogoeva
15:00 — 15:15 Variability in Gibbs energy of tRNA molecules in mitochondrial genomes of Chordates: neutral selection or evolution towards optimization of translation?\ K. Ushakova, A. A. Mikhaylova, A. G. Mikhaylova, D. Knorre, I. Mazunin, A. Reymond, K. Gunbin, K. Popadin
15:15 — 15:30 Research of molecular mechanisms of pathogenesis of depression: bioinformatical analysis of transcriptomic data.\ I.N. Vlasov1*, E.A. Bondarenko1, M.I. Shadrina1, P.A. Slominskiy1
15:30 — 15:45 Analysis of the molecular mechanisms of Pinus sylvestris and Hordeum vulgare adaptation to the action of low doses of ionizing radiation\ P. Volkova, G. Duarte, E. Kazakova
15:45 — 16:00 Detection of pathogenic mutations in patients with non-coronary heart diseases by targeted NGS\ D. Yermakovich, L. Sivitskaya, T. Vaikhanskaya, A. Liaudanski, N. Danilenko
16:00 — 16:15 Systems analysis of the genes responding to chilling stress in Arabidopsis thaliana L.\ A. Zlobin, N. Omelyanchuk, V. Mironova
16:15 — 16:45 Coffee-break
16:45 — 17:15 Closing ceremony and Awards of best reports