Selected courses (content, sample slides, etc.).
Computational Systems Biology
- Genomic Regulatory Signals (example slides)
- Mechanisms of transcriptional control
- The databases on transcriptional regulation
- Conformational and physicochemical context-dependent DNA properties used for functional sites recognition and analysis. B-DNA Video Internet system.
- Gene expression control on the mRNA translation stage
- The recognition of promoters
- Analysis and recognition of transcription factor binding sites
- Computational Genomics (example slides)
- Internet-resources for DNA sequence search and analysis
- General subject of bioinformatics
- Databases on Genes and Genomes
- Repeats in DNA, formal description and analysis
- Consensus, position weight matrices, sequence alignment methods
- Machine learning methods overview: hidden Markov models, neural networks, genetic algorithm
- Methods for eukaryotic gene structure annotation
- Statistical approaches used for different recognition techniques: accuracy comparison
- Investigation of qualitative and quantitative characteristics of transcriptome
- Gene networks (example slides)
- Reconstruction gene network and analysis of their properties
- The arhitecture of gene network
- Apoptosis gene network
- The development networks
- Gene network complexity of prokaryotes and eukaryotes
- The principle of organization of metabolic networks