Dear colleagues!
From 24 to 25 June 2014 Institute of Internal Medicine SB RAMS (Novosibirsk , Russia), Institute of Medical Genetics SB RAMS (Tomsk, Russia) and the Institute of Cytology and Genetics SB RAS (Novosibirsk, Russia ) conduct an international symposium “Human Genetics” (ISHG2014).
Symposium “Human Genetics” will take place as a part of the Multiconference “Bioinformatics and Systems Biology” in conjunction with the conference BGRS \ SB- 2014. Advances in modern medicine are based on discoveries in the basic sciences with evidential base. Personalized medicine and translational medicine are based on the data of molecular diagnostic, genetics, and pharmacogenomics. The symposium “Human Genetics” within Multiconference “Bioinformatics and Systems Biology” affords ground for communication between specialists from different fields of science and allows integrating obtained data using bioinformatics and experimental approaches for investigation of systems and processes in medicine.
Chairs: Mikhail Ivanovich Voevoda, director of the FSBI IPM SB RAMS, сorresponding member of the RAMS, Valery Pavlovich Puzyrev, director of the IMG SB RAMS, full member of the RAMS.
Human genetics has become the focus of all achievements of genetics and other “omic” technologies. Actual trends in applied aspects are: translational medicine, personalized medicine, ethnogenomics.
Achievements in human genetics have become the basis for genomic medicine. Translational medicine, figuratively defined as “from base pairs to bedside”, just started its progress in relation to widespread multifactorial diseases, whereas most success has been achieved for Mendelian disorders, which, however, account for only 1% of all human diseases.
Main idea of personalized medicine is well known for two thousand years, and genomic technologies added only a little to its effectiveness. Still open is the question: in which cases medical care should be individualized, and in which cases it should be universal.
Ethnogenomics is one of the most advanced parts of human genetics in Russia, but inter-population analysis has been performed mostly for those genome regions which mark evolutionary and migration events. Little is known about population specific features of complex diseases susceptibility structure, and this knowledge is unconvincing.
In the last ten years, epigenetics becomes leading topic in human and medical genetics, so do the studies for genome structure variability in somatic cells, not only in carcinogenesis (traditionally) but also in other multifactorial diseases.
It is supposed that these and other related topics will be discussed in the section reports.
Sections:
o Translational medicine.
o High-throughput sequencing in clinical medicine
o Medical genetics
o Ethnogenetics