Conference program

THE Conference program (pdf): A PRELIMINARY VERSION

July 24: Arrival
July 25: Registration from 10:00
Opening Ceremony at 14:00.
A preliminary working schedule by sections:
July 25 – 26: COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS;
July 27: COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS;
July 28: POSTER SESSION;
July 29: COMPUTATIONAL EVOLUTIONARY BIOLOGY;
NEW APPROACHES TO ANALYSIS OF BIOMOLECULAR DATA AND PROCESSES
July 30: COMPUTATIONAL SYSTEM BIOLOGY
July 28: INTAS-FP6 Workshop on “EU-NIS Partnering in Bioinformatics”

COMPUTATIONAL STRUCTURAL AND FUNCTIONAL GENOMICS

ORAL REPORTS

Abnizova I., te Boekhorts R., Gilks W.
MRC-BSU Cambridge, University of Hertfordshire Hatfield, UK
SOME WAYS TO INFER A DNA FUNCTION FROM THE SEQUENCE INFORMATION

1Alexeevski A.V., 1Lukina E.N., 2Salnikov A.N., 1Spirin S.A.
1Belozersky Institute, Moscow State University, Moscow, Russia.
2Department of Computational Mathematics and Cybernetic, Moscow State University, Moscow, Russia
DATABASE OF LONG TERMINAL REPEATS IN HUMAN GENOME: STRUCTURE AND SYNCHRONIZATION WITH MAIN GENOME ARCHIVES

1Astakhova T.V, 1Petrova S.V, 2Tsitovich I.I., 1Roytberg M.A.
1Institute of Mathematical Problems in Biology RAS, Puschino, Russia
2Institute of Information Transmission Problems RAS, Moscow, Russia
RECOGNITION OF CODING REGIONS IN GENOME ALIGNMENT

Borlak J.T.
Fraunhofer Institute of Toxicology and Experimental Medicine, Hannover, Germany
THE CHALLENGE OF OMICS SCIENCES: \”TURNING DATA INTO KNOWLEDGE\”

Bucher Ph.
Swiss Institute of Bioinformatics, Epalinges s/Lausann, Switzerland
MODELLING TRANSCRIPTION FACTOR BINDING SITES WITH HIGH-THROUGHPUT SELEX DATA

1Brahmachari S. K., 1Grover D, 2Majumder P.P, 1Mukerji M.
1Institute of Genomics and Integrative Biology, CSIR, Delhi, India.
2Anthropology and Human Genetics Unit, Indian Statistical Institute, Kolkata 700 108, India
NON-RANDOM DISTRIBUTION OF ALU ELEMENTS IN HUMAN: NOVEL INSIGHTS FROM ANALYSIS OF THE COMPLETE GENOME

1Brok-Volchanski A.S., 1Purtov Yu.A., 1Lukyanov V.I., 1Kostyanicina E.G.,
1Antipov S.S., 2Deev A.A., 1Ozoline O.N.
1Institute of Cell Biophysics RAS, Pushchino, Moscow region, Russia
2 Institute of Theoretical and Experimental Biophysics RAS, Pushchino, Moscow region, Russia
GENOME-WIDE MAPPING OF POTENTIALLY TRANSCRIBED REGIONS BY NEW PROMOTER-SEARCH ALGORITHM

1Choi C.H., 2Kalosakas G., 2Rasmussen K.O., 2Bishop A.R., 1Usheva A.
1Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
2Los Alamos National Laboratory, Los Alamos, NM, USA
ACCURATE PREDICTION OF DNA OPENING PROFILES BY PEYRARD-BISHOP NONLINEAR DYNAMIC SIMULATIONS

Dadashev S.Ya., Grishaeva T.M., Bogdanov Yu. F.
N.I.Vavilov Institute of General Genetics RAS, Moscow, Russia
DEVELOPMENT OF A METHOD FOR IN SILICO IDENTIFICATION OF DNA SEQUENCES PARTICIPATING IN MEIOTIC CHROMOSOME SYNAPSIS AND RECOMBINATION

Ignatieva E. V., Oshchepkov D.Yu., Levitsky V.G., Vasiluev G.V., Klimova N.V., Busygina T.V., Merkulova T.I. Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
COMPARISON OF THE RESULTS OF SEARCH FOR THE SF- 1 BINDING SITES IN THE PROMOTER REGIONS OF THE STEROIDOGENIC GENES, USING THE SITEGA AND SITECON METHODS

Kersey, P.J., Morris L., Faruque N., Kulikova, T., Whitfield E., Apweiler R.
EMBL Outstation, European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
GENOME REVIEWS: INTGERATED VIEWS OF COMPLETE GENOMES

1Kochetov A.V., 2Sarai A., 1Kolchanov N.A.
1Institute of Cytology and Genetics, Novosibirsk, Russia
2Kyushu Institute of Technology, Dept. Biochemical Engineering and Science, Iizuka, Japan
TRANSLATIONAL POLYMORPHISM AS A POTENTIAL SOURCE OF EUKARYOTIC PROTEINS VARIETY

Levitsky V.G., Proscura A.P., Podkolodnaya O.A., Ignatieva E.V., Ananko E.A.
Institute of Cytology & Genetics SB RAS, Novosibirsk, Russia
NUCLEOSOME FORMATION POTENTIAL OF THE GENE REGULATORY REGIONS

1Makeev V.J., 2Lifanov A.P, .3Nazina A.G, 3Papatsenko D.A.
1Scientific Center “Genetika”, Moscow, Russia.
2Engelhardt Institute of Molecular Biology, Moscow, Russia
3Department of Biology, New York University, New York, USA
DISTANCE PREFERENCES IN DISTRIBUTION OF BINDING MOTIFS AND HIERARCHICAL LEVELS IN ORGANIZATION OF TRANSCRIPTION REGULATORY INFORMATION

1Makunin I.V., 1Stephen S, 1Pheasant M., 2Bejerano G., 2Kent J.W., 3Haussler H., 1Mattick J.S.
1ARC Special Research Centre for Functional and Applied Genomics, Institute for Molecular Bioscience, University of Queensland, Brisbane, Australia
2Department of Biomolecular Engineering, University of California Santa Cruz, Santa Cruz, CA, USA
3Howard Hughes Medical Institute, University of California Santa Cruz, Santa Cruz, CA, USA
EXTREMELY CONSERVED NON-CODING SEQUENCES IN VERTEBRATE GENOMES

1Orlov Yu.L., 2Potapov V.N., 1Poplavsky A.S.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
COMPUTER ANALYSIS OF GENOMIC SEQUENCE COMPLEXITY: NEW APPLICATIONS

1Sarai A., 1Ahmad S. , 2Gromiha M.M., 3Kono H.
1Dept. Bioscience & Bioinformatics, Kyushu Institute of Technology, Iizuka, Japan
2Computational Biology Research Center, AIST, Tokyo, Japan
3Neutron Science Research Center and Center for Promotion of Computational Science and Engineering Japan Atomic Energy Research Institute, Kyoto, Japan
GENOME-SCALE PREDICTION OF TRANSCRIPTION FACTORS AND THEIR TARGETS

Vorobjev Y. N.
Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia
MODELING OF CONTEXT-DEPENDENT CONFORMATIONAL PARAMETERS OF DNA DUPLEXES

Xia X.
Department of Biology, University of Ottawa, Ottawa, Canada
A PECULIAR CODON USAGE PATTERN REVEALED AFTER REMOVING THE EFFECT OF DNA METHYLATION

POSTER PRESENTATIONS

1Albini G., 1Chetouani F., 1Rouille S., 1Karsenty E., 2Thomas B., 1Legeai F., 1Samson D., 5Pereira L., 3Arcade A., 3Joets J., 2Scala D., 5Viara E., 4Barillot E., 1Duclert A.
1 GenoplanteInfo, Unite de Recherche Genomique-Info, INRA, EVRY, France
2 RhoBioInf, Evry Cedex, France
3 INRA, Ferme du Moulon, Gif-sur-Yvette, France
4 Institut Curie, Paris, France
5 SYSRA, EVRY, France
GpiMap, AN ENVIRONMENT FOR GENETIC/PHYSICAL MAP DATA MANAGEMENT, VISUALIZATION AND COMPARATIVE ANALYSIS

1Boeva V.A., 2Regnier M., 3Makeev V.J.
1Moscow State University, Moscow, Russia
2INRIA Rocquencourt, Le Chesnay, France
3State Center GosNIIGenetika, Moscow, Russia
ALGORITHM FOR SEARCHING FOR HIGHLY DIVERGENT TANDEM REPEATS IN DNA SEQUENCES, STATISTICAL TESTS, AND BIOLOGILAL APPLICATION IN DROSOPHILA MELANOGASTER GENOME

1Denisov S.V., 1,2,3Gelfand M.S.
1M.V. Lomonosov Moscow State University, Moscow, Russia
2Institute for Information Transmission Problems RAS, Moscow, Russia
3State Scientific Center GosNIIGenetika, Moscow, Russia
CONSERVATION OF ALTERNATIVE SPLICING REGULATORY SIGNAL UGCAUG IN MOUSE AND HUMAN GENOMES

Frenkel F.E., Chaley M.B., Korotkov E.V., Skryabin K.G.
Centre “Bioengineering” RAS, Moscow, Russia
INFORMATIONAL ASPECTS OF THE LATENT TRIPLET PERIODICITY ANALYSIS

1Fursov M.Yu., 1Baksheyev D.G., 1Rodionov K.V., 1Golubitskii A.A.,
2Saraev D.V., 2Denisov S.I., 2Blinov V.M.
1Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia
2State Research Center of Virology and Biotechnology “VECTOR”, Koltsovo, Russia
A PRACTICAL METHOD FOR MAXIMUM EXACT MATCHES IN LARGE GENOMES

Ignatieva E.V., Ananko E.A., Podkolodnaya O.A., Stepanenko I.L., Khlebodarova T.M., Merkulova T.I., Podkolodny N.L., Grigorovich D.A., Poplavsky A.S., Naumochkin A.N., Pozdnyakov M.A., Romashchenko A.G., Kolchanov N.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
TRANSCRIPTION REGULATORY REGIONS DATABASE (TRRD): ITS STATUS IN 2004

Ignatieva E. V., Levitsky V.G., Vasiliev G.V., Klimova N.V., Busygina, T.V., Merkulova T.I. Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
DISTRIBUTION OF THE SF-1 SITES IN THE GENOMIC SEQUENCES PREDICTED BY THE SITEGA METHOD AND THEIR EXPERIMENTAL VERIFICATION

Ishchukov I.M., Likhoshvai V.A., Matushkin Yu.G.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
A NEW ALGORITHM FOR RECOGNIZING THE OPERON STRUCTURE OF PROKARYOTES

Kamzolova S. G., Sorokin A. A., Dzhelyadin T. R., Osypov A. A., Beskaravainy P. M.
Institute of Cell Biophysics of RAS, Pushchino Moscow region, Russia
ANALYSIS OF OLIGONUCLEOTIDE COMPOSITION IN DNA OF E. COLI GENOME AND PROMOTER SITES

Kamzolova S.G., Sorokin A.A., Dzhelyadin T.R., Beskaravainy P.M., Osypov A.A.
Institute of Cell Biophysics of RAS, Pushchino, Moscow region, Russia
ELECTROSTATIC PROPERTIES OF E.COLI GENOME DNA

Katokhin A.V., Levitsky V.G., Oshchepkov D.Yu., Poplavsky A.S., Furman D. P.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
ANALYSIS OF NUCLEOSOME FORMATION POTENTIAL AND CONFORMATIONAL PROPERTIES OF HUMAN J1-J2 TYPE ALPHA SATELLITE DNA

1Kazakov A.E., 2Kalinina O.V., 3Permina E.A., 1,2,3Gelfand M.S.
1Institute for Information Transmission Problems RAS, Moscow, Russia
2Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia
3State Scientific Center GosNIIGenetika, Moscow, Russia
BACTERIAL METAL RESISTANCE SYSTEMS REGULATED BY TRANSCRIPTION REGULATORS OF THE MERR FAMILY

Khlebodarova T.M., Podkolodnaya O.A., Ananko E.A., Stepanenko I.L., Ignatieva E.V., Podkolodny N.L., Pozdnyakov M.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
TRRD_ARTSITE DATABASE: STRUCTURES OF TRANSCRIPTION FACTOR BINDING SITES

Khlebodarova T.M., Podkolodnaya O.A., Ananko E.A., Ignatieva E.V.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
COMPARISON OF THE STRUCTURES OF IN VITRO SELECTED AND NATURAL BINDING SITES OF TRANSCRIPOTION FACTORS

1,2Kondrakhin Yu.V., 1Poplavsky A.S., 1Podkolodnaya O.A., 1Ignatieva E.V., 1Ananko E.A., 1Khlebodarova T.M., 1Stepanenko I.L., 1Podkolodny N.L. 1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
TFBSANALYZER: A WEB TOOLKIT FOR ANALYSIS AND PREDICTION OF TRANSCRIPTION FACTOR BINDING SITES

1Konstantinov Yu.M. , 2Poplavsky A.S.
1Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
ANALYSIS OF PLANT MITOCHONDRIAL GENOME ORGANIZATION: CHARACTERISTICS OF REPEATS AND SEQUENCE COMPLEXITY

1Kosmodemiansky I.A., 1,2,3Gelfand M.S., 1,3Mironov A.A.
1Department of Bioengineering and Bioinformatics , Moscow State University, Moscow, Russia
2Institute for Information Transmission Problems RAS, Moscow, Russia
3State Scientific Center GosNIIGenetika, Moscow, Russia
MANUAL CURATION OF EST LIBRARIES BY TISSUE SPECIFICITY AND CELL ORIGIN

Leontiev L.A., Shirshin M.A., Lyubetsky V.A.
Institute for Information Transmission Problems RAS, Moscow, Russia
DETECTION OF CLASSICAL ATTENUATION IN BACTERIAL GENOMES

Levitsky V.G., Katokhin A.V., Furman D.P.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
ANALYSIS OF PERIODICITIES IN THE DINUCLEOTIDE CONTEXT OF NUCLEOSOMAL DNA USING THE METHOD PHASE

Levitsky V.G., Ignatieva E.V., Busygina T.V., Merkulova T.I.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
ANALYSIS OF THE CONTEXT FEATURES OF SF-1 BINDING SITE AND DEVELOPMENT OF A CRITERION FOR SF-1 REGULATED GENE RECOGNITION BY THE SITEGA METHOD

1 Pichueva A.G.

1 LevitskyV.G., 1 Kochetov A.V., 2Milanesi L.

1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Istitute of Advanced Biomedical Tecnologies, CNR, Milan, Italy
DNA NUCLEOSOME ORGANIZATION OF THE FUNCTIONAL GENES REGIONS AND ITS RELATION TO GENE EXPRESSION LEVEL

Leyfer D., Weng Z.
Boston University, Boston, USA
GENOME-WIDE IDENTIFICATION OF TRANSCRIPTIONAL MODULES BY CIS-ELEMENT AND EXPRESSION CLUSTERING

Lyubetsky V.A., *Seliverstov A. V.
Institute for Information Transmission Problems RAS, Moscow, Russia
AMINO ACID BIOSYNTHESIS ATTENUATION IN BACTERIA

Mishchenko E.L., Kondrahin Yu.V., Podkolodnaya O.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
СOMPUTER ANALYSIS AND PREDICTION OF POTENTIAL IRON-RESPONSIVE ELEMENTS IN 5′ AND 3′ UTR OF EUKARYOTE GENES TRANSCRIPTS

Oparina N., Rychkov A., Mashkova T.
Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
THE NEW APPROACH OF BOTH NEW AND OLD SEGMENTAL DUPLICATIONS SEARCH: REPETITIVE DNA AS A MOLECULAR ARCHAEOLOGY TOOL

Orlov Yu.L., Levitsky V.G.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
NUCLEOSOME POSITIONING SIGNAL ANALYSIS

1Orlov Yu.L., 1Proscura A.L., 2Vityaev E.E., 3 Arrigo P.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
3ISMAC, Genova, Italy
CONTEXT FEATURES OF TRANSCRIPTION FACTOR BINDING SITE SEQUENCES: RELATION TO DNA-BINDING DOMAIN CLASSIFICATION

Oshchepkov D.Yu., Grigorovich D.A,. Ignatieva E.V., Khlebodarova T.M.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
SITECON: A TOOL FOR DETECTING CONSERVATIVE CONFORMATIONAL AND PHYSICOCHEMICAL PROPERTIES IN TRANSCRIPTION FACTOR BINDING SITES ALIGNMENTS AND FOR SITE RECOGNITION

Ponomarenko M.P., Ponomarenko J.V.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
A DATABASE ON DNA SEQUENCE/ACTIVITY RELATIONSHIPS: APPLICATION TO PHYLOGENETIC FOOTPRINTING

Proskura A.L., Oshchepkov D.Yu., Pozdnyakov M.A., Ignatieva E.V.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
SREBP BINDING SITES: CONTEXT FEATURES AND ANALYSIS OF GENOME DISTRIBUTION BY THE SITECON METHOD

1Samsonova A., 2Dieterich C., 2Vingron M., 1Brazma A.
1EMBL-EBI, Wellcome Trust Genome Campus, Cambridge, UK
2 Max-Planck-Institute for Molecular Genetics, Berlin, Germany
SEARCH FOR REGULATORY MOTIFS IN DROSOPHILA MELANOGASTER GENOME

1Saraev D.V., 1Dzhekshenbaeva G.K., 2Baksheyev D.G., 2Rodionov K.V., 2Golubitskii A.A., 2Fursov M.Yu., 2Golosov I.S., 3Kisselev L.L., 1Blinov V.M.
1State Research Center of Virology and Biotechnology “Vector”, Koltsovo, Russia
2Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia
3Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
LONG SEGMENTAL REPEATS IN HUMAN GENOME: DENSITY, DISTRIBUTION, STRUCTURE

1Stavrovskaya E.D., 23Mironov A.A.
1Department of Information Technologies, Peoples’ Friendship University of Russia, Moscow, Russia
2State Scientific Center GosNIIGenetika, Moscow, Russia.
3Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia
BINARY TREE FOR CLUSTERING OF REGULATORY SIGNALS

1,2Titov I.I., 2Vorobiev D.G. , 1Palyanov A.Yu.
1Novosibirsk State University, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
WEB-SERVER GARNA FOR RNA STRUCTURE ANALYSIS: ITS STATE IN 2004

1Vasyunina E.A., 1,2Rogozin I.B., 1Sinitsina O.I., 1Plaksina A.S.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, MD, USA
THEORETICAL AND EXPERIMENTAL STUDY OF MUTATIONS INDUCED BY 8-OXOGUANINE

1Vishnevsky O.V., 1Ignatieva E.V., 2Arrigo P.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2ISMAC, Genova, Italy
THE ARGO_SITES: AN ANALYSIS AND RECOGNITION OF THE TRANSCRIPTION FACTOR BINDING SITES BASED ON SETS OF DEGENERATE OLIGONUCLEOTIDE MOTIFS

Vitreschak A., Noe L., Kucherov G.
INRIA-Lorraine/LORIA, Villers-les-Nancy, France
COMPUTER ANALYSIS OF MULTIPLE REPEATS IN BACTERIA

1,2Walker N.J, 1Sharrocks A.D, 1,2Attwood T. K.
1School of Biological Sciences, University of Manchester, UK
2Department of Computer Science, University of Manchester, UK
USE OF AN INTEGRATED RULE SYSTEM FOR IDENTIFICATION OF THE TRANSCRIPTION FACTOR BINDING SITES MCM 1 AND FKH 2 IN S.CEREVISIAE

Yu R., Tan E.C.
School of Computer Engineering, Nanyang Technological University, Singapore, Singapore
APPLICATION OF TIME-FREQUENCY ANALYSIS IN EXON CLASSIFICATION

COMPUTER DEMONSTRATIONS

Golubitskii A.A.
Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia
A PRACTICAL METHOD FOR MAXIMUM EXACT MATCHES IN LARGE GENOMES: UniPro Genome Browser – tool for visual analysis and annotation of large genomes

Rodionov K.V.
Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia
A PRACTICAL METHOD FOR MAXIMUM EXACT MATCHES IN LARGE GENOMES: UniPro DPview – a tool for finding and analyzing matches between genomes

Xia X.
Department of Biology, University of Ottawa, Ottawa, Canada
DAMBE: AN INTEGRATED ENVIRONMENT FOR DATA ANALYSIS IN MOLECULAR BIOLOGY AND EVOLUTION

1Zykovich A.S., 2Axenovich T.I.
1Novosibirsk State University, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
DEVELOPMENT OF METHOD FOR IN SILICO MAPPING OF QUANTITATIVE TRAIT LOCI

COMPUTATIONAL STRUCTURAL AND FUNCTIONAL PROTEOMICS

ORAL REPORTS

12Chekmarev S. F., 2Palyanov A.Yu., 3Krivov S. V., 24Titov I.I., 3,5Karplus M.
1Institute of Thermophysics SB RAS, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
3Laboratoire de Chimie Biophysique, ISIS, Universite Louis Pasteur, Strasbourg, France
4Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
5Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA KINETICS OF PROTEIN FOLDING AND MISFOLDING: LATTICE SIMULATIONS AND ANALYTIC MODEL

Efremov R.G. Volynsky P.E., Nolde D.E., Vereshaga Y.A., Konshina A.G., Simakov N.A., Arseniev A.S.
Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia
MEMBRANE PROTEINS: THE NEW INSIGHTS via COMPUTATIONAL EXPERIMENTS

1Ivanisenko V.A., 2Pintus S.S., 2Krestyanova M.A., 2 DemenkovP.S., 2Znobisheva E.K., 2Ivanov E.E., 1Grigorovich D.A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
PDBSITE, PDBLIGAND AND PDBSITESCAN: A COMPUTATIONAL WORKBENCH FOR THE RECOGNITION OF THE STRUCTURAL AND FUNCTIONAL DETERMINANTS IN PROTEIN TERTIARY STRUCTURES COMBINED WITH PROTEIN DRAFT DOCKING

1Kalinina O.V., 1Novichkov P.S., 1,2Mironov A.A., 2,3Gelfand M.S., 1Rakhmaninova A.B.
1 Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia. 2 State Scientific Center GosNIIGenetika, Moscow, Russia.
3 Institute for Problems of Information Transmission RAS, Moscow, Russia.
SDPPRED: A METHOD FOR PREDICTION OF AMINO ACID RESIDUES THAT DETERMINE DIFFERENCES IN FUNCTIONAL SPECIFICITY OF HOMOLOGOUS PROTEINS AND ITS APPLICATION TO THE MIP FAMILY OF MEMBRANE TRANSPORTERS

2Ko, J., 1Andre, P., 1Murga, L.F., 1Ondrechen, M.J.
1Department of Chemistry and Chemical Biology and Institute for Complex Scientific Software, Northeastern University, Boston, Massachusetts, USA
2NSF-ROA awardee on leave from Department of Chemistry, Indiana University of Pennsylvania, Indiana, Pennsylvania , USA
STATISTICAL METRICS FOR PROTEIN ACTIVE SITE PREDICTION WITH THEMATICS

1Kuznetsov V.A., 2Pickalov V.V, 3 Knott G.D., 4Kanapin A.A.
1CIT/NIH & SRA International, Inc. Bethesda, MD, USA
2Institute of Theoretical and Applied Mechanics SB RAS, Novosibirsk, Russia
3Civilized Software, Inc., Silver Spring, MD, USA
4EMBL-EBI Wellcome Trust Genome Campus, Hinxton, UK
ANALYSIS OF PROTEOME COMPEXITY BASED ON COUNTING DOMAIN-TO-PROTEIN LINKS

1Milanesi L.,1Merelli I., 2Pattini L., 2Cerutti S.
1Institute of Advanced Biomedical Technologies, CNR, Segrate (Milan), Italy.
2Department of Biomedical Engineering, Polytechnic University of Milan, Milan, Italy.
REPRESENTATION AND MODELLING OF PROTEIN SURFACE DETERMINANTS

Rahmanov S.V., Makeev V.Yu.
Laboratory of Bioinformatics, GosNIIGenetika, Moscow, Russia
CONSTRUCTING DETAILED KNOWLEDGE-BASED ATOMIC POTENTIALS FOR WATER IN PROTEINS

Ramachandran S. Jain P., Sachdeva G.
G.N. Ramachandran Knowledge Center for Genome Informatics, Institute of Genomics and Integrative Biology, Delhi, India
MINING FROM COMPLETE PROTEOMES TO IDENTIFY ADHESINS AND ADHESIN-LIKE PROTEINS: A RAPID AID TO EXPERIMENTAL RESEARCHERS

Ramensky V.E., Tumanyan V.G.
Engelhardt Institute of Molecular Biology of Russian Academy of Sciences, Moscow, Russia
MUTANT PROTEIN STRUCTURES REVEAL MOLECULAR MECHANISMS OF INHERITED DISEASES

Shaitan K.V.
M.V. Lomonosov Moscow State University, Moscow, Russia
MOLECULAR DYNAMICS SIMULATIONS FOR LARGE SERIES OF PEPTIDES (COMPARATIVE STUDY)

Surya pavan Y. , Mitra C.K.
Department of Biochemistry, University of Hyderabad, Hyderabad , India
A MARKOV MODEL FOR PROTEIN SEQUENCES

Turutina V.P., Korotkov E.V., Laskin A.A.
Bioengineering Center RAS, Moscow, Russia
LATENT PERIODICITY OF THE PROTEIN FAMILIES

POSTER PRESENTATIONS

Afonnikov D.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
Novosibirsk State University, Novosibirsk, Russia
PREDICTING CONTACT NUMBERS OF AMINO ACID RESIDUES USING A NEURAL NETWORK MODEL

Amirova S.R., Machavariani M., Filatov I.V., Milchevsky Ju.V., Esipova N.G., Tumanyan V.G.
Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
COMBINED APPROACH TO PROTEIN SECONDARY STRUCTURE PREDICTION

Andrianov A.M.
Institute of Bioorganic Chemistry of National Academy of Sciences, Minsk, Republic of Belarus
STRUCTURE AND POLYMORPHISM OF THE HIV-1 PRINCIPAL NEUTRALIZING EPITOPE

1Antyufeev V.S., 2Nikolaev S.V.
1Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
A FAST PROCEDURE FOR MODELING OF PROTEASOMAL PROTEIN DEGRADATION IN VITRO

Bachinsky A.G., Solovyev V.V.
Softberry Inc., Mount Kisco, NY, USA
Permanent address: SRC VB “Vector”, Koltsovo, Novosibirsk region, Russsia
NEW APPROACHES TO ANALYSIS OF PROTEIN STRUCTURE AND FUNCTION

Belenikin M.S.
Lomonosov Moscow State University, Department of Chemistry, Moscow, Russia
MOLECULAR MODELING AND COMPARATIVE ANALYSIS OF AMINO-TERMINAL DOMAIN OF NMDA IONOTROPIC GLUTAMATE RECEPTORS

Chelobanov B.P., 1Ivanisenko V.A., Kharkova M.V., Laktionov P.P., Rykova E.Yu., Vlassov V.V
Institute of Chemical Biology and Fundamental Medicine SB RAS, Russia
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
IDENTIFICATION AND ANALYSIS OF CELL SURFACE NUCLEIC ACIDS-BINDING PROTEINS

Chumakov M.I., Burmatov A.V., Bogdanov V.I., Volohina I.V.
Institute of Biochemistry and Physiology of Plants and Microorganisms RAS, Saratov, Russia
EXPERIMENTAL AND COMPUTER EVALUATION OF AGROBACTERIAL SST-DNA BINDING VIRE2 PROTEIN ABILITY TO INTERACT WITH LIPID MEMBRANES

Ershova A.S., 1Alexeevski A.V., 1Spirin S.A., Karyagina A.S.
Institute of Agricultural Biotechnology, Russian Academy of Agricultural Sciences Moscow, Russia;
1Belozersky Institute, Moscow State University, Moscow, Russia
COMMON STRUCTURAL FEATURES OF HOMEODOMAINS AND HOMEODOMAIN-DNA COMPLEXES

Filatov I.V., Milchevsky Ju.V., Esipova N.G., Tumanyan V.G.
Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
COMPUTATION OF THE THREE DIMESIONAL STRUCTURE OF THE HUMAN TYPE(III) COLLAGEN

Gariev I.A., Uporov I.V., Varfolomeev S.D.
Moscow State University, Moscow, Russia
SEARCHING STRUCTURAL PROTEIN DATABASES FOR EZYMATIC ACTIVE SITES BY 3D PATTERNS

1Karasev V.A., 1Luchinin V.V, 2 Stefanov V.E.
1Saint-Petersburgh State Electrotechnical University “LETI”, Saint-Petersburgh, Russia
2 Saint-Petersburgh State University, Saint-Petrsburgh, Russia
SYMMETRY AND SPATIAL STRUCTURE OF THE CANONICAL SET OF AMINO ACIDS

Kolesov G, Mirny L.A.
Harvard-MIT Division of Health Sciences and Technology, MIT, Cambridge, USA
FROM PROTEIN SEQUENCE TO PROTEIN SPECIFICITY: COMPLETELY AUTOMATED DISCOVERY AND MAPPING OF SPECIFICITY DETERMINING RESIDUES

1Kosinsky Yu.A., 1Nolde D.E., 2Tsivkovskii R., 1Arseniev A.S., 1Lutsenko S., 1Efremov R.G.
1M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia.
2Department of Biochemistry and Molecular Biology, Oregon Health and Science University, Portland OR, USA
MOLECULAR MODELING OF THE NUCLEOTIDE-BINDING DOMAIN OF THE WILSON’ DISEASE PROTEIN: THE ATP-BINDING SITE AND DOMAIN DYNAMICS

Kuznetsov V.A.
CIT/NIH & SRA International, Inc. Bethesda, MD, USA
VALIDATION OF RANDOM BIRTH-DEATH MODEL OF EVOLUTION OF PROTEOME COMPLEXITY

1Litvinov I.I., 2Mironov A.A, 3Finkelstein A.V., 1Roytberg M.A.
1Institute of Mathematical Problems in Biology RAS, Puschino, Russia
2Moscow State University, Department of Biotechnology and Bioinformatics, Moscow, Russia
31Institute of Protein Research RAS, Puschino, Russia
INFORMATION ABOUT SECONDARY STRUCTURE IMPROVES QUALITY OF PROTEIN ALIGNMENT

Naumoff D.G.
State Institute for Genetics and Selection of Industrial Microorganisms, Moscow, Russia
THE ALPHA-GALACTOSIDASE SUPERFAMILY: SEQUENCE BASED CLASSIFICATION OF ALPHA-GALACTOSIDASES AND RELATED GLYCOSIDASES

Nikolaev S.V., Afonnikov D.A..
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
INTER-SUBUNIT CONTACTS OF THE PROTEASOMAL ALPHA-SUBUNITS AS DETERMINANTS OF PARALOG GROUPS

Nizolenko L. Ph., Bachinsky A. G., Yarygin A. A., Naumochkin A. N., Grigorovich D. A.
SRC “Vector”, Koltsovo, Novosibirsk, Russia.
PROTEIN FAMILY PATTERNS BANK PROF_PAT. CURRENT STATUS

2Palyanov A.Yu., 3Krivov S. V., 24Titov I.I., 3,5Karplus M., 12Chekmarev S. F.
1Institute of Thermophysics SB RAS, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
3Laboratoire de Chimie Biophysique, ISIS, Universite Louis Pasteur, Strasbourg, France
4Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
5Department of Chemistry & Chemical Biology, Harvard University, Cambridge, MA, USA PROTEIN FOLDING AND MISFOLDING: A BBIFURCATION STUDY OF A LATTICE MODEL

1Palyanov A.Yu., 1,2Titov I.I.
1Novosibirsk State University, Novosibirsk, Russia
2 Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
STRUCTURAL MEMORY OF A LATTICE PROTEIN

1Perevalov D.S., 2Davydov O.M., 3Tatur S.V., 3Lenskiy S.V.
1Institute of Mathematics and Mechanics Urals Branch of RAS, Yekaterinburg, Russia
2Chelyabinsk State University, Chelyabinsk, Russia
3Urals State University, Yekaterinburg, Russia
ON ENERGY DISTRIBUTION OF RANDOM WALKS WITH CONSTRAINTS AND GEOMETRICAL COMPLEXITY OF POLYMERS

1Pintus S.S., 2Ivanisenko V.A.
1Novosibirsk State University, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
A MOLECULAR MECHANISM FOR THE STRUCTURE-FUNCTIONAL ALTERATIONS IN MUTANT FORMS OF HUMAN P53 PROTEIN

1,2Polyansky A.A, 2Volynsky P.E, 2Efremov R.G.
1Biological Department, M.V.Lomonosov Moscow State University, Moscow, Russia
2M.M. Shemyakin and Yu.A. Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia
COMPUTER SIMULATIONS OF ANIONIC UNSATURATED LIPID BILAYER: A BASE SYSTEM TO STUDY PEPTIDE-MEMBRANE INTERACTIONS

1Ragulina L.E., 2Makeev V.Ju., 3Esipova N.G., 3Tumanyan V.G., 2Bogush V.G., 2Debabov V.G., 3Nikitin A.M.,3Vlasov P.K.
1Moscow Institute of Physics and Technology, Moscow, Russia
2State Scientific Center “GosNIIGenetika”, Moscow, Russia
3Engelhardt Institute of Molecular Biology RAS, Moscow, Russia
PERIODICAL PATTERNS IN SEQUENCES OF SPIDROINS 1 AND 2 AND SECONDARY STRUCTURE PREDICTION

Sadovskaya N.S.
GosNIIGenetika, Moscow, Russia
BENCHMARKING OF TRANSMEMBRANE HELIX PREDICTION SERVERS

Skarina T., Evdokimova E., Yakunin A., Khachatryan A., Pennycooke M., Guido V., Guthrie J., Xu X., Semesi A., Gu J., Kudritska M., Egorova O., Gorodichtchenskaia E., Yee A., Savchenko A., Arrowsmith C.H., Edwards A.M.
Ontario Centre for Structural Proteomics, University of Toronto, University Health Network, Toronto, ON, Canada
STRUCTURAL AND FUNCTIONAL ANALYSIS OF POORLY CHARACTERIZED PROTEIN FAMILIES AT THE ONTARIO CENTRE FOR STRUCTURAL PROTEOMICS

1,2Tchugunov A.O., 3Chavatte P., 1Efremov R.G.
1 Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry RAS, Moscow, Russia
2 Department of Bioengineering, Biological Faculty, M.V. Lomonosov Moscow State University, Moscow, Russia
3 Faculte des Sciences Pharmaceutiques et Biologiques, Lille Cedex, France
MOLECULAR MODELING OF HUMAN MT1 AND MT2 MELATONIN RECEPTORS

1,2Titov I.I., 2Vorobiev D.G., 1Palyanov A.Yu.
1Novosibirsk State University, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
WEB-SERVER GARNA FOR RNA STRUCTURE ANALYSIS: ITS STATE IN 2004

1Varlamova E.S., 1,2Afonnikov D.A.
1Novosibirsk State University, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
IMPROVED PREDICTION OF PROTEIN CONTACT MAPS USING INFORMATION ON RESIDUE CONTACT NUMBERS

COMPUTER DEMONSTRATION

Gribkov M.A., Korotkova M.A.
Moscow Engineering-Physics Institute (State University), Moscow, Russia
A SYSTEM FOR COMPLEX ANALISYS OF PROTEIN MACROMOLECULES SPATIAL STRUSTURES

COMPUTATIONAL EVOLUTIONARY BIOLOGY

ORAL REPORTS

1 Bazykin G.A., Ogurtsov A.Y., 2Kondrashov A.S.
1 Dept. of Ecology and Evolutionary Biology, Princeton University, Princeton, NJ, USA,
2 National Center for Biotechnology Information, NIH, Bethesda, Maryland, USA
CHANGE IN CPG CONTEXT IS A LEADING CAUSE OF CORRELATION BETWEEN RATES OF NON-SYNONYMOUS AND SYNONYMOUS SUBSTITUTIONS IN RODENTS

Gelfand M. S.
Institute for Information Transmission Problems RAS, Moscow, Russia
State Scientific Center GosNIIGenetika, Moscow, Russia
Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia
EVOLUTION OF BACTERIAL REGULATORY SYSTEMS

1 Nishio Y., 2Nakamura Y., 1Usuda Y., 3Kawarabayasi, Y., 4Yamagishi A., 1Kimura E., 1Matsui K., 5Sugimoto S., 6Kikuchi H, 2Ikeo K., 2Gojobori T.
1Institute of Life Sciences, Ajinomoto Co., Inc., Kawasaki, Japan
2Center for Information Biology and DNA Data Bank of Japan, National Institute of Genetics, Mishima, Japan
3 Research Center for Glycoscience, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba, Japan
4Department of Molecular Biology, Tokyo University of Pharmacy and Life Science, Hachioji , Japan
5Fermentation & Biotechnology Laboratories, Ajinomoto Co., Inc., Kawasaki, Japan
6National Institute of Technology and Evaluation, Shibuya , Japan
COMPARATIVE COMPLETE GENOME SEQUENCE ANALYSIS OF CORYNEBACTERIA

Stamatakis A.P., Ludwig T., Meier H.
Department of Computer Science, Technische Universitat Munchen
Department of Computer Science, Ruprecht-Karls Universitat Heidelberg
COMPUTING LARGE PHYLOGENIES WITH STATISTICAL METHODS: PROBLEMS AND SOLUTIONS

1Sherbakov D.Yu. , 2Martens K., 2Schoen I.
1Limnological Institute SB RAS, Irkutsk, Russia
2Royal Belgian Institute for Natural sciences, Brussels, Belgium
EXPLAINING APPARENT STALL OF MOLECULAR EVOLUTION IN ASEXUAL OSTRACOD DARWINULA: MODELLING APPROACH

1,2Vershinin A.V., 2Allnutt T.R., 2Knox M.R., 2Ambrose M.J., 2Ellis T.H.N.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2John Innes Centre, Norwich, UK
DOMINANT MODE IN PISUM DIVERSITY GENERATION: WHAT IS THE IMPACT OF TRANSPOSABLE ELEMENTS?

Kapitonov V.V., Jurka J.
Genetic Information Research Institute, Mountain View, California, USA
MOLECULAR PALEONTOLOGY OF DNA TRANSPOSONS IN EUKARYOTIC GENOMES

Wyrwicz L.S., Rychlewski L.
Bioinformatics Laboratory, BioInfoBank Institute, Poznan, Poland
SCANNING THE HUMAN GENOME FOR REGULATORY ISLANDS WITH PHYLOGENETIC FOOTPRINTING ALGORITHM

Zhivotovsky L.A.
N.I.Vavilov Institute of General Genetics RAS, Moscow, Russia
DATING POPULATION EXPANSION BASED ON STR VARIATION WITHIN Y-CHROMOSOME SNP-HAPLOGROUPS

Zhou Z., Kwoh C.K.
Bioinformatics Research Centre, School of CE, Nanyang Technological University, Singapore
AN EVOLUTIONARY LINEAGE FOR INTRON LOSS/GAIN IN FIVE EUKAYOTIC GENOMES

POSTER PRESENTATIONS

1,2Babenko V.N., 1Sverdlov A., 1,2Rogozin I.B., 2Koonin E.V. 1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda MD, USA
2Institute of Cytology and Genetics RAS, Novosibirsk, Russia
EVOLUTION OF GENE STRUCTURE IN EUKARYOTIC GENOMES

3Beresikov E., 1Novikova O., 2Makarevich I., 1Lashina V., 3Plasterk R.,1Blinov A.G.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Department of Agronomy and Plant Genetics, University of Minnesota, St. Paul, USA
3Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht, The Netherlands EVOLUTIONARY RELATIONSHIPS AND DISTRIBUTION OF NON-LTR RETROTRANSPOSONS IN EUKARYOTES

Chaley M.B., Frenkel F.E., Korotkov E.V., Skryabin K.G.
Centre “Bioengineering” RAS, Moscow, Russia
RELATIONSHIPS BETWEEN GENERAL CLASSIFICATION OF GENES’ LATENT TRIPLET PERIODICITY AND THE UNIVERSAL PHYLOGENETIC TREE

1Favorov, A.V., 2Favorova O.O., 2Andreewski, T.V., 2Sudomoina, M.A., 2Alekseenkov, A.D., 2Kulakova, O.G., 2Boiko, A.N., 2Gusev, E.I., 3Parmigiani, G., 4 Ochs, M.F.
1 State Scientific Centre “GosNIIGenetika”, Moscow, Russia
2 Russian State Medical University, Moscow, Russia
3 Johns Hopkins University, Baltimore, MD, USA
4 Fox Chase Cancer Center, Philadelphia, PA, USA
MCMC METHOD HAS FOUND THAT MULTIPLE SCLEROSIS IS ASSOCIATED WITH TWO THREE-GENES COMBINATIONS

1Gerasimova A.V., ,2,3Ravcheyev D.A., 1,2,3Gelfand M.S., 2 Rakhmaninova A.B.
1 State Scientific Center “GosNII Genetica”, Moscow, Russia
2 Department of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia
3 Institute For Information Transmission Problems RAS, Moscow, Russia
COMPARATIVE GENOMIC ANALYSIS OF RESPIRATION SWITCH IN GAMMA-PROTEOBACTERIA

Hakobyan G.O., Margaryan T.V.
THE DISTANCE FUNCTION FOR COMPUTING THE CONTINUOUS DISTANCE OF BIOPOLYMER SEQUENCES
Department of Physics, Yerevan State University, Yerevan, Armenia

1Katyshev A.I., 2Rogozin I.B, 1Konstantinov Y.M.
1Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
GENOME-WIDE IDENTIFICATION OF MITOCHONDRIAL DNA TOPOISOMERASE I IN ARABIDOPSIS

Korostishevsky M., Bonne-Tamir B.
Dept. of Human Genetics and Molecular medicine, Sackler School of Medicine, Tel-Aviv University, Ramat-Aviv, Israel
A SIMPLE TEST FOR LINKAGE DISEQUILIBRIUM BETWEEN A MARKER ALLELE AND A GENE MUTATION IN HETEROZYGOTE CARRIERS

1Korostishevsky M, 2Burd A, 2Mester D, 1Bonne’-Tamir B, 2Nevo E, 2Korol A.
1Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
2Institute of Evolution, University of Haifa, Haifa, Israel
EVOLUTIONARY TREE RECONSTRUCTION AND TRAVELING SALESMAN PROBLEM: A POWERFUL ALGORITHM FOR SHAGGY TREES

1,2Kovaleva G.Y., 1Mironov A.A., 2Gelfand M.S.
1Moscow State University, Department of Bioengeneering and Bioinformatics, Moscow, Russia
2Institute for Information Transmission Problems, RAS, Moscow, Russia
THE CONSERVATION OF TRANSCRIPTION FACTOR-BINDINS SITES IN SACCHAROMYCES GENOMES

1Novikova O., 2Fursov M., 3Beresikov E., 1Blinov A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Novosibirsk Center of Information Technologies “UniPro”, Novosibirsk, Russia
3Hubrecht Laboratory, Netherlands Institute for Developmental Biology, Utrecht, The Netherlands. NEW LTR RETROTRANSPOSABLE ELEMENTS FROM EUKARIOTIC GENOMES

1Salina E.A., 1Adonina I.G., 2Lim Y.K., 1Scherban’ A.B., 1Vatolina T.Yu., 2Leitch A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Queen Mary University, London, UK
EVOLUTION OF DIPLOID PROGENITORS OF COMMON WHEAT ON THE BASE OF RAPD AND SUBTELOMERIC REREATS ANALYSIS

Triboy T.I., Sherbakov D.Yu.
Limnological Institute SB RAS, Irkutsk, Russia
COUNTERING COORDINATED AMINO ACID SUBSTITUTIONS IN PHYLOGENETIC ANALYSIS

1Watanabe M., 2Goto N., 1Watanabe Y., 1Nishiguchi S., 1Shimada K., 2Yasunaga T., 1Yamanishi H.
1Hirakata Ryoikuen, Osaka, Japan
2Department of Human Genome Research, Genome Information Research Center, Osaka University, Osaka, Japan
EVOLUTION OF INTERLEUKIN-18 BINDING PROTEIN FAMILY

COMPUTER DEMONSTRATION

1Korostishevsky M, 2Burd A, 2Mester D, 1Bonne’-Tamir B, 2Nevo E, 2Korol A.
1Department of Human Genetics and Molecular Medicine, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
2Institute of Evolution, University of Haifa, Haifa, Israel
EVOLUTIONARY TREE RECONSTRUCTION AND TRAVELING SALESMAN PROBLEM: A POWERFUL ALGORITHM FOR SHAGGY TREES

COMPUTATIONAL SYSTEM BIOLOGY

ORAL REPORTS

1Chaouiya C., 2Sanchez L., 1 Thieffry D.
1Laboratoire de Genetique et Physiologie du Developpement, Marseille, France
2Centro de Investigaciones Biologicas, Madrid, Spain
FROM GRADIENTS TO STRIPES: A LOGICAL ANALYSIS OF THE GENETIC NETWORK CONTROLLING EARLY DROSOPHILA SEGMENTATION

1Gor, V., 1Shapiro B.E., 2Jonsson, H., 1Heisler, M, 1Venugopala Reddy, G., 1Meyerowitz EM, 3Mjolsness E.
1California Institute of Technology, Pasadena, CA, USA
2Lund University, Lund, Sweden
3University of California, Irvine, CA, USA
A SOFTWARE ARCHITECTURE FOR DEVELOPMENTAL MODELING IN PLANTS: THE COMPUTABLE PLANT PROJECT

Hofestaedt R., Chen M.
Bioinformatics / Medical Informatics, Technische Fakultaet, Universitaet Bielefeld, Bielefeld, Germany
METABOLIC PATHWAY PREDICTION/ALIGNMENT

2,3 Likhoshvai V.A., 1Demidenko G.V., 1Fadeev S.I.
1Sobolev Institute for Mathematics SB RAS, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
MODELLING OF SUBSTANCE SYNTHESIS PROCESS WITHOUT BRANCHING BY THE DELAY EQUATION

Mironov A.A.
Moscow State University, Department of Bioengineering and Bioinformatics, Moscow, Russia
State Scientific Centre “GosNIIGenetica”, Moscow, Russia
RIBOSWITCHES – A NOVEL TYPE OF REGULATORY SYSTEM

1 Nedosekina E. A., 1Ananko E. A., 1,2Likhoshvai V.A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
COMPUTER MODELING OF THE FUNCTION OF TRANSCRIPTION FACTORS DURING MACROPHAGE ACTIVATION
1 Nutsch T., 2 Marwan W., 3 Oesterhelt D., 1 Gilles E.D.
1 Max-Planck-Institute for Dynamics of Complex Technical Systems, Magdeburg, Germany 2 Science & Technology Research Centre, University of Hertfordshire, U. K.
3 Max-Planck-Institute for Biochemistry, Martinsried, Germany
A COHERENT KINETIC MODEL OF SENSING AND RESPONSE IN HALOBACTERIUM SALINARIUM PHOTOTAXIS BASED ON THE MECHANISM OF FLAGELLAR MOTOR SWITCHING

Omelyanchuk L.V., Gunbin K.V.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
ELEMENTARY MODULE, RECOGNIZING MORPHOGENETIC GRADIENTS IN THE TISSUES

Omelianchuk N.A., Mironova V.V., Poplavsky A.S., Kukeeva Yu.A., Podkolodny N.L., Kolchanov N.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
AGNS: ARABIDOPSIS GENENET SUPPLEMENTARY DATABASE

Peng F., Pio F.
Department of Molecular Biology & Biochemistry, Simon Fraser University, Burnaby, British Columbia, Canada
PROTEIN-PROTEIN INTERACTION NETWORK OF APOPTOSIS SIGNALING PATHWAYS AND ITS USAGE TO IDENTIFY APOPTOTIC REGULATORY ELEMENTS

1Samsonova M., 1Surkova S., 2Jaeger J., 2Reinitz J.
1 Department of Computational Biology, Center for Advanced Studies, St. Petersburg State Polytechnical University, St. Petersburg, Russia
2 Department of Applied Mathematics and Statistics, and Center for Developmental Genetics, Stony Brook University, Stony Brook, NY, USA
QUANTITATIVE APPROACH TO THE FUNCTIONAL GENOMICS OF DEVELOPMENT

Srividhya, K.V., Krishnaswamy, S.
Bioinformatics Centre, School of Biotechnology, Madurai Kamaraj University, Tamil Nadu, India
A SIMULATION MODEL OF ENVZ-OMPR TWO COMPONENT SYSTEM IN ESCHERICHIA COLI

Tchuraev R.N.
Institute of Biology, Ufa Research Center, Russian Academy of Sciences, Ufa, Russia
PRINCIPLES OF ORGANIZATION AND LAWS OF FUNCTIONING IN CONTROL GENE NETWORKS

1,2Zabarovsky E.R., 1Kashuba V.I., 1Li J., 1Kutsenko A.S., 1Protopopov A.I., 1Petrenko L, 1Wang F., 3Senchenko V.N., 4Kadyrova E., 1Zabarovska V.I., 2Muravenko O.V., 2Zelenin A.V., 2Kisselev L.L., 1Winberg G., 1Ernberg I., 4Braga E., 5Lerman M.I., 1Klein G.
1 MTC and CGB, Karolinska Institute, Stockholm, Sweden
2EIMB, RAS, Moscow, Russia
3Bioengineering Center and EIMB, RAS, Moscow, Russia
4Russian State Genetics Center, Moscow, Russia
5 FCI-NCI, Frederick, USA
RESTRICTION SITE TAGGED PASSPORTS AND MICROARRAYS FOR ANALYSIS OF COMPLEX BIOLOGICAL SYSTEMS

POSTER PRESENTATIONS

Abdeev R.M.
Vavilov Institute of General Genetics RAS, Moscow, Russia
Center for Theoretical Problems of Physical-Chemical Bases of Pharmacology RAS, Moscow, Russia
A SYSTEMIC APPROACH TO COMPLEX, MULTI-FACTOR AUTOIMMUNE DISEASES AIMED AT CREATION OF ADEQUATE MODELS OF PATHOLOGIES (E.G. PSORIASIS)

Ananko E.A., Nedosekina E.A, Oshchepkov D.Yu., Lokhova I.V., Likhoshvai V.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
EBV INFECTION AND EBV TRANSFORMATION: RECONSTRUCTION OF GENE NETWORKS IN THE GENENET SYSTEM AND SEARCHING FOR REGULATORY POINTS

1Fadeev S.I., 1Gainova I.A., 1Berezin A.Yu., 2Ratushny A.V., 2Matushkin Yu.G., 2,3Likhoshvai V.A.
1Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
DETERMINATION OF STATIONARY SOLUTIONS IN GENE NETWORK MODELS BY HOMOTOPY METHOD

1Fadeev S.I., 2Osokina V.A., 3,4Likhoshvai V.A.
1Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
3Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
4Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
ABOUT COMPUTATIONAL RESEARCH OF MATHEMATICAL MODELS OF HYPOTHETICAL GENE NETWORKS BY PARAMETER CONTINUATION.

Galimzyanov A.V.
Institute of Biology, Ufa Research Center, Russian Academy of Sciences, Ufa, Russia
ON ONE ALGORITHM FOR MODELING PASSIVE TRANSPORT IN CELL SETS OF ARBITRARY CONFIGURATION

1Golubyatnikov V.P., 2Makarov E.V.
1Institute of Mathematics SB RAS, Novosibirsk, Russia
2Siberian Department of International Institute for Nonlinear Science RAS, Novosibirsk, Russia
CLOSED TRAJECTORIES IN THE GENE NETWORKS

1Golubyatnikov V.P. , 1Volokitin E.P., 2,3Likhoshvai V.A., 4Osipov A.F.
1Institute of Mathematics SB RAS, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
4Novosibirsk State University, Novosibirsk, Russia
HOPF BIFURCATION AND CLOSED TRAJECTORIES IN THE GENE NETWORKS

Gorbunov K.Yu., Lyubetsky V.A.
Institute for Information Transmission Problems of the Russian Academy of Sciences, Moscow, Russia
A MODEL OF TRYPTOPHAN BIOSYNTHESIS REGULATION

Gunbin K.V., Omelyanchuk L.V., Ananko E.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
TWO GENE NETWORKS UNDERLYING THE FORMATION OF THE ANTERIOR-POSTERIOR AND DORSO-VENTRAL WING IMAGINAL DISC COMPARTMENT BOUNDARIES IN DROSOPHILA MELANOGASTER

2Gursky V.V., 1Kozlov K.N., 2Samsonov A.M.
1Dept. of computational biology, State Polytechnical University, St.Petersburg, Russia
2A.F. Ioffe Physico-technical Institute of the Russian Academy of Sciences, St.Petersburg, Russia
COMBINED OPTIMIZATION TECHNIQUE FOR BIOLOGICAL DATA FITTING

Guryeva Ya.P., Stepanenko I.L., Likhoshvai V.A.
Institute of Cytology and Genetics, SB RAS, Novosibirsk, Russia
MATHEMATICAL MODEL OF THE GENE NETWORK OF TNF?-INDUCED NF-kappaB ACTIVATION

1V.V.Kogai, 1S.I.Fadeev, 2,3V.A.Likhoshvai
1Sobolev Institute of Mathematics SB RAS, Novosibirsk, Russia
2Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
ABOUT NUMERICAL INVESTIGATION OF AUTO-OSCILLATIONS IN HYPOTHETICAL GENE NETWORKS

Kolpakov F.A.
Biosoft.Ru/DevelopmentOnTheEdge.com, Novosibirsk, Russia;
Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia.
BIOUML – OPEN SOURCE EXTENSIBLE WORKBENCH FOR SYSTEMS BIOLOGY

1,2,Kondrakhin Yu.V., 1Podkolodnaya O.A., 1Turnaev I.A., 1Kolchanov N.A.
1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
STATISTICAL ANALYSIS OF MICROARRAY DATA: IDENTIFICATION AND CLASSIFICATION OF HUMAN CELL CYCLE GENES

1Lashin S.A., 1,2Likhoshvai V.A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
EVOLUTIONARY ALGORITHMS FOR MATHEMATICAL MODELS OF GENE NETWORKS IDENTIFICATION

Lashin S.A., Likhoshvai V.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
EXPLICIT INTEGRAL METHOD FOR NONLINEAR DYNAMIC MATHEMATICAL MODELS IDENTIFICATION

1,2 Likhoshvai V.А.
1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
ON THE STATIONARY POINTS OF REGULATORY CONTOURS OF GENE NETWORKS

Mironova V.V., Omelianchuk N.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
GENE NETWORK OF THE ARABIDOPSIS DEVELOPING SHOOT MERISTEM AND ITS DESCRIPTION IN THE GENENET COMPUTER SYSTEM

2,4Peshkov, 1,3Likhoshvai V.A., 1Matushkin Yu.G., 2Fadeev S.I.
1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Mathematical Institute of SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
4Novosibirsk State University, Novosibirsk, Russia
ON RESEARCH INTO HYPOTHETICAL NETWORKS OF ECOLOGICAL NATURE

Pisarev A., Blagov M., Samsonova M.
Department of Computational Biology, Center for Advanced Studies, St. Petersburg State Polytechnical University, St. Petersburg, Russia
METHOD FOR INTEGRATION OF DATABASES WITH COMMON SUBJECT DOMAINS

1,2Podkolodny N.L., 1Ananko E.A., 1Loktev K.A., 1Rasskazov D.A., 1,3Miginsky D.S., 3Zapadinskaya A.E.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Institute of Computational Mathematics and Mathematical Geophysics SB RAS, Novosibirsk, Russia
3Novosibirsk State University, Novosibirsk, Russia
GENENET: VISUAL MODELING AND ANALYSIS OF GENE NETWORKS

1Ratushny A.V., 1,2Likhoshvai V.A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
TOWARDS COMPUTER DYNAMIC MODELING OF WHOLE CELL

Shen L., Tan E.C.
School of Computer Engineering, Nanyang Technological University, Nanyang Avenue, Singapore, Singapore
EFFICIENT ALGORITHM FOR GENE SELECTION USING PLS-RLSC

Surkova S. Yu., Samsonova M.G.
St.Petersburg State Polytechnical University, St.Petersburg , Russia
TEMPORAL AND SPATIAL PRECISION IN FORMATION OF SEGMENTATION GENE EXPRESSION DOMAINS IN DROSOPHILA

Turnaev I.I., Ananko E.A., Podkolodnaya O.A.
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
CENTRAL REGULATION OF THE GENE NETWORK OF THE CELL CYCLE IN MAMMALS: AN ANALYSIS OF CLOSED REGULATORY LOOPS

1Vasilenko N.L., 2,4Balueva K.E., 1,3Likhoshvai V.A., 2Nevinsky G.A., 1Matushkin Yu.G.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Institute of Chemical Biology and Fundamental Medicine SB RAS, Novosibirsk, Russia
3Ugra Research Institute of Information Technologies, Khanty-Mansyisk, Russia
4Novosibirsk State University, Novosibirsk, Russia
CONSTRUCTION OF MOLECULAR TRIGGER IN E. COLI

1Vladimirov N.V., 1,2Likhoshvai V.A
Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 STOCHASTIC MODEL OF TRANSLATION ELONGATION BASED ON CONTINUOUS TIME MONTE CARLO METHOD

Zhang C., Li S.
Institute of Bioinformatics, MOE Key Laboratory of Bioinformatics, Tsinghua University, Beijing, P. R. China
MODELING OF NEURO-ENDOCRINE-IMMUNE NETWORK VIA SUBJECT ORIENTED LITERATURE MINING

COMPUTER DEMONSTRATION

Kolpakov F.A.
Biosoft.Ru/DevelopmentOnTheEdge.com, Novosibirsk, Russia
Design Technological Institute of Digital Techniques SB RAS, Novosibirsk, Russia
BIOUML – OPEN SOURCE EXTENSIBLE WORKBENCH FOR SYSTEMS BIOLOGY

1Tarasov D.S., 2Leontiev A.Yu., 1Akberova N.I
Kazan State University, Kazan, Russia
Kazan State Academy of Veterinary Medicine, Kazan, Russia
A LANGUAGE FOR MODELING GENETIC REGULATION IN PROCARYOTES

NEW APPROACHES TO ANALYSIS OF BIOMOLECULAR DATA AND PROCESSES

ORAL REPORTS

Akbari A., Algregtsen F.
Department of Informatics, University of Oslo, Oslo, Norway
AUTOMATIC LANE DETECTION AND SEPARATION IN ONE DIMENSIONAL DNA GEL IMAGES

1Binder H., 1Kirsten T., 1Loeffler M., 1Preibisch St., 1,2Stadler P.
1Interdisciplinary Centre for Bioinformatics, University of Leipzig, Germany
2 Institute for Informatics, University of Leipzig, Germany
SEQUENCE-SPECIFIC SENSITIVITY OF OLIGONUCLEOTIDE PROBES – A MOLECULAR VIEW ON RNA/DNA HYBRIDISATION ON MICROARRAYS AND CONSEQUENCES FOR GENE EXPRESSION ANALYSIS AND CHIP DESIGN

Blagov M.S., Poustelnikova E.G., Pisarev A.S., Myasnikova E.M., Samsonova M.G.
St.Petersburg State Polytechnical University, St.Petersburg, Russia
A SYSTEM FOR ON-LINE PROCESSING OF IMAGES OF GENE EXPRESSION PATTERNS

Fattore M., Arrigo P.
CNR ISMAC, Section of Genoa, Genova, Italy
TOPICAL CLUSTERING OF BIOMEDICAL ABSTRACT by SELF ORGANIZING MAPS

1Favorov A.V., 1,2,3Gelfand M.S., 1Gerasimova A. V., 1,3Mironov A.A., 1Makeev V.J.
1 State Scientific Centre “GosNIIGenetica”, Moscow, Russia
2 Institute for Problems of Information Transmission RAS, Moscow, Russia
3 Dept. of Bioengineering and Bioinformatics, Moscow State University, Moscow, Russia
GIBBS SAMPLER FOR IDENTIFICATION OF SYMMETRICALLY STRUCTURED, SPACED DNA MOTIFS WITH IMPROVED ESTIMATION OF THE SIGNAL LENGTH AND ITS VALIDATION ON THE ARCA BINDING SITES

1Frisman E. Ya., 2Zhdanova O. L.
1Complex Analysis of Regional Problems Institute FEB RAS, Birobidzhan, Russia
2Institute of Automation and Control Processes FEB RAS, Vladivostok, Russia
MATHEMATICAL MODELLING AND ANALYSIS OF THE FIXATION PROCESS OF DISCRETE GENETIC STRUCTURES IN A MENDELIAN ONE-LOCUS POPULATION OF DIPLOID ORGANISMS

1,2Gorban A.N., 1Popova T.G., 3Zinovyev A.Yu.
1Institute of Computational Modeling SB RAS, Krasnoyarsk, Russia
2Institute of polymer physics, ETH, Zurich, Switzerland
3Institut des Hautes Etudes Scientifiques, Bures-sur-Yvette, France
SEVEN CLUSTERS AND UNSUPERVISED GENE PREDICTION

Lyubetsky V.A., V’yugin V.V.
Institute for Information Transmission Problems RAS, Moscow, Russia
MEASURING THE DISSIMILARITY BETWEEN GENE AND SPECIES TREES, THE QUALITY OF A COG

1Myasnikova E.M., 2Reinitz J.
1St.Petersburg State Polytechnical University, St.Petersburg, Russia
2 University at Stony Brook, New York, USA
DETERMINATION OF THE DEVELOPMENTAL AGE OF A DROSOPHILA EMBRYO FROM CONFOCAL IMAGES OF ITS SEGMENTATION GENE EXPRESSION PATTERNS

Noe L., Kucherov G. LORIA/INRIA-Lorraine, Villers-les-Nancy, France
YASS: ENHANCING THE SENSITIVITY OF DNA SIMILARITY SEARCH

1Novichkov P., 2Brudno M., 1Mironov A.
1Moscow State University, Faculty of Bioengineering & Bioinformatics, Moscow, Russia
2Stanford University, Department of Computer Science Clark Center, Stanford, CA , USA
MAXIMAL INFORMATION CONTENT SEEDS FOR SEQUENCE ALIGNMENT

1Pozdnyakov M.A., 1Orlov Yu.L., 1Vishnevsky O.V., 1Proscura A.L., 2Vityaev E.E., 3Arrigo P.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Sobolev Institute of Mathematics, Novosibirsk, Russia
3ISMAC, Genova, Italy
ANALYSIS OF GENE REGULATORY SEQUENCES BY KNOWLEDGE DISCOVERY METHODS

Shelenkov A.A., Chaley M.B., Korotkov E.V.
Center of Bioengineering RAS, Moscow, Russia
REVELATION AND CLASSIFICATION OF DINUCLEOTIDE PERIODICITY OF BACTERIAL GENOMES USING THE METHODS OF INFORMATION DECOMPOSITION AND MODIFIED PROFILE ANALYSIS

1,2Deyneko I.V., 3Kel A.E., 3Wingender E., 2Gossling F., 2Blocker H., 2,4Kauer G.
1 Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2 Department of Genome Analysis, GBF, Braunschweig, Germany
3 BIOBASE GmbH, Wolfenbuettel, Germany
4 FH Oldenburg/Ostfriesland/Wilhelmshaven, Germany
SIGNAL THEORY – AN ALTERNATIVE PERSPECTIVE OF PATTERN SIMILARITY SEARCH

BIOINFORMATICS AND EDUCATION

POSTER PRESENTATIONS

1,2 Afonnikov, D.A., 1 Ivanisenko, V.A., 1 Ignatieva, E.V., 1 Levitsky, V.G., 1 Likhoshvai, V.A., 1 Nikolaev, S.V., 1 Orlov, Yu.L., 1 Titov, I.I.,1 Kolchanov N.A.
1Institute of Cytology and Genetics SB RAS, Novosibirsk, Russia
2Novosibirsk State University, Novosibirsk, Russia
A CURRICULUM FOR BIOINFORMATICS AT THE CHAIR FOR INFORMATIONAL BIOLOGY, THE NOVOSIBIRSK STATE UNIVERSITY

Korotkova M. A.
Moscow Engineering Physics Institute, Moscow, Russia
BIOINFORMATICS TEACHING IN MOSCOW ENGENEERING PHYSICS INSTITUTE (STATE UNIVERSITY)

Lohmann M., Schomburg D.
Cologne University Bioinformatics Center, Cologne, Germany
RESEARCH AND TEACHING AT THE COLOGNE UNIVERSITY BIOINFORMATICS CENTER (CUBIC) – MOLECULAR NETWORKS IN ORGANISMS